Votre recherche pour: ENZO LIFE SCIENCES

Référence Produit: (ENZOENZ42834)

Fournisseur: ENZO LIFE SCIENCES

Description: Fluorescein-12-UTP is ideal for <i>in vitro</i> transcription reactions catalysed by T3, T7, or SP6 RNA polymerases and reverse transcriptase to produce fluorophore-labeled RNA transcripts. RNA-based probes can be used to identify complementary sequences by<i> in situ</i> hybridisation to fixed cells and tissues by direct or indirect fluorescence detection or by membrane hybridisation procedures.

UOM: 1 * 250 Nmo

*Promo

Fournisseur: ENZO LIFE SCIENCES

Description: Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serine binds to the GSK-3β priming phosphate position and prevents binding of alternative substrates. In addition to insulin signaling, GSK-3β participates in the Wnt signaling pathway, where it forms a complex with axin, beta-catenin and adenomatous polyposis coli (APC) protein. In the presence of Wnts, GSK-3β is unable to phosphorylate beta-catenin, which leads to stabilization of beta-catenin. The Wnt pathway inactivates GSK-3β via the proteins, Dishevelled and FRAT, which disrupt the interaction of GSK-3β with axin, beta-catenin, and APC. Clinically, there is considerable interest in GSK-3β inhibitors because they may mimic the effect of insulin or reduce the hyperphosphorylation of Tau that is observed in Alzheimer's Disease.

Référence Produit: (ENZOALX522057C050)

Fournisseur: ENZO LIFE SCIENCES

Description: Produced in HEK 293 cells. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused to the Fc portion of human IgG1.

UOM: 1 * 50 µG

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Référence Produit: (ENZOALX746256C100)

Fournisseur: ENZO LIFE SCIENCES

Description: Inactive (neutral) control.

UOM: 1 * 100 µG

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Référence Produit: (ENZOENZABS2260100)

Fournisseur: ENZO LIFE SCIENCES

Description: Recommended Applications: ELISA, IP, WB

Species reactivity: Human, Mouse

UOM: 1 * 100 µG

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Fournisseur: ENZO LIFE SCIENCES

Description: Ceramide synthase inhibitor

Référence Produit: (ENZOALX201144C025)

Fournisseur: ENZO LIFE SCIENCES

Description: Produced in <i>E. coli</i>.

UOM: 1 * 25 µG

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Référence Produit: (ENZOENZABS2575000)

Fournisseur: ENZO LIFE SCIENCES

Description: Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain.

UOM: 1 * 5 mL

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Référence Produit: (ENZOADI900155)

Fournisseur: ENZO LIFE SCIENCES

Description: For the quantitative determination of TGF-β1 in culture supernatants, plasma, and serum of human, mouse, rat, and cow origin.

UOM: 1 * 1 KIT

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Référence Produit: (ENZOBMLAR1120100)

Fournisseur: ENZO LIFE SCIENCES

Description: Adrenergic receptor ligand.

UOM: 1 * 100 mg

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Référence Produit: (ENZOENZABS2190100)

Fournisseur: ENZO LIFE SCIENCES

Description: Recommended Applications: ELISA, ICC, IHC, WB

Species reactivity: Mammalian

UOM: 1 * 100 µl

*Promo

Fournisseur: ENZO LIFE SCIENCES

Description: Necroptosis inhibitor

Référence Produit: (ENZOENZ42819)

Fournisseur: ENZO LIFE SCIENCES

Description: Bio-7-dATP (Biotin-7-2’-deoxyadenosine-5’-triphosphate) can replace dATP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase.

UOM: 1 * 50 Nmo

*Promo

Fournisseur: ENZO LIFE SCIENCES

Description: Nitrone spin trap for the specific <i>in vivo</i> or <i>in vitro</i> detection of short-lived superoxide, hydroxyl and thiyl radicals.

Fournisseur: ENZO LIFE SCIENCES

Description: A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis.

Référence Produit: (ENZOALX307071C020)

Fournisseur: ENZO LIFE SCIENCES

Description: Isoins(1,4,5)P3/PM (caged) ≥98% (par HPLC)

UOM: 1 * 20 µG

*Promo