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Image Unavailable-50008.

5,5’-Dimethyl BAPTA tetrapotassium salt ≥95% (par CCM) chélateur d'ions, pour détermination du calcium

Référence Produit: (50008.)
Fournisseur: Biotium
Description: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.
UOM: 1 * 100 mg
Product Image-552-0184

TLC plates, cellulose MN 400, AVICEL®

Fournisseur: MACHEREY-NAGEL
Description: These TLC plates and sheets are prepared by hydrolysis of high purity cellulose with HCl. They are used for carboxylic acids, lower alcohols, urea and purine derivatives.

Image Unavailable-ENZOBMLPG0480001

13,14-Dihydro-prostaglandin E1 ≥98% (par CCM)

Fournisseur: ENZO LIFE SCIENCES
Description: Circulating metabolite of PGE1 in man. Vasodilator equipotent with PGE12. Inhibits human platelet aggregation. Antimitotic activity.

Image Unavailable-BOSSBS-8546R-FITC

Anti-KRIT1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-8546R-FITC)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8546R-A350

Anti-KRIT1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Référence Produit: (BOSSBS-8546R-A350)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLG2440050

Simvastatin ≥98% (par CCM)

Fournisseur: ENZO LIFE SCIENCES
Description: HMG-CoA reductase inhibitor

Product Image-ENZOALX550228M025

5-Nitro-6,7-dichloro-1,4-dihydro-2,3-quinoxalinedione ≥98% (par CCM)

Fournisseur: ENZO LIFE SCIENCES
Description: Potent and selective NMDA receptor glycine site antagonist.

Image Unavailable-BOSSBS-8546R-CY7

Anti-KRIT1 Rabbit Polyclonal Antibody (Cy7®)

Référence Produit: (BOSSBS-8546R-CY7)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8546R

Anti-KRIT1 Rabbit Polyclonal Antibody

Référence Produit: (BOSSBS-8546R)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8546R-HRP

Anti-KRIT1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-8546R-HRP)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8546R-A555

Anti-KRIT1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-8546R-A555)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8546R-A647

Anti-KRIT1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-8546R-A647)
Fournisseur: Bioss
Description: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
UOM: 1 * 100 µl
Product Image-ACE-129-3020

Avantor® ACE® C18-AR, colonnes UHPLC, 5 µm

Fournisseur: Avantor
Description: La phase Avantor® ACE® C18-AR utilise un ligand spécialement développé combinant une chaîne C18 avec une fonctionnalité phényle intégrale, associant ainsi les avantages des caractéristiques C18 et phényle en une seule phase. On peut s'en servir pour les séparations sur colonne C18 "standard", mais il est également recommandé pour les séparations qui impliquent des composés contenant des fonctions aromatiques.

Product Image-552-0007

Nanomat 4

Référence Produit: (552-0007)
Fournisseur: CAMAG
Description: Le Nanomat 4 est utilisé pour une application facile d'échantillons sous forme de spots sur des couches TLC et HPTLC. Un système d'encoche garantit que le positionnement de l'échantillon répond aux exigences du balayage automatique avec un densitomètre. Les échantillons sont distribués dans des volumes de 0,5 à 5 µl avec des capillaires jetables chargés dans le support capillaire universel (552-0044) à l'aide du guide capillaire (552-0039).
UOM: 1 * 1 Pce
Product Image-BOHLV1830-07

Armoire dessiccateur, SICCO Star Thermo

Référence Produit: (BOHLV1830-07)
Fournisseur: Bohlender
Description: Cadre en aluminium avec système de chambre à 2 vitres (à l’intérieur verre, à l’extérieur verre acrylique), quatre étagères en polycarbonate inclus, peut être équipé avec jusqu’à 26 étagères. Chauffage intégré (850 W) avec capteur de température et ventilateur. Un branchement électrique (230 V/ 50 Hz) est nécessaire.
UOM: 1 * 1 Pce
Product Image-390-1352

VWR® INCU-Line® ILPR Premium, Incubateurs réfrigérés avec la technologie Peltier

Fournisseur: VWR Collection
Description: Les incubateurs refroidis par la technologie Peltier se caractérisent par une excellente stabilité et uniformité de la température. Ils ont un bon rendement énergétique et sont respectueux de l'environnement, avec un faible niveau sonore, et ils fonctionnent presque sans vibrations car aucun compresseur n'est installé. Pas de déshumidification des échantillons en raison de la chambre fermée. Ces modèles, à convection forcée, offrent une plage de température comprise entre 0 et +70 °C (max. 20 °C en dessous de la température ambiante) et sont dotés d'une chambre intérieure en acier inoxydable (DIN 1.4301) et d'un boîtier en acier inoxydable, d'une porte extérieure pleine et d'une porte intérieure en verre. Les modèles PREMIUM disposent d'un menu intuitif et d'un logiciel facile à utiliser et d'un port USB pour le téléchargement de données sur une clé USB et pour le chargement des programmes. Ils peuvent être connectés à un réseau Ethernet ou Wi-Fi pour un contrôle à distance depuis n'importe quel ordinateur, et les utilisateurs peuvent recevoir des notifications sur les paramètres sélectionnables par e-mail.

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