Votre recherche pour: ENZO LIFE SCIENCES

Référence Produit: (ENZOADI900142)

Fournisseur: ENZO LIFE SCIENCES

Description: For the quantitative determination of human Osteopontin in culture supernatants, milk, plasma, and urine. Cited sample type includes serum.

UOM: 1 * 1 KIT

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Référence Produit: (ENZOADI900070)

Fournisseur: ENZO LIFE SCIENCES

Description: For the quantitative determination of Cysteinyl Leukotrienes (LTC4/D4/E4) in culture supernatants and urine from any species.

UOM: 1 * 1 KIT

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Référence Produit: (ENZOADI900028A)

Fournisseur: ENZO LIFE SCIENCES

Description: For the quantitative determination of human leptin in culture supernatants, plasma, and serum.

UOM: 1 * 1 KIT

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Référence Produit: (ENZOADI900013)

Fournisseur: ENZO LIFE SCIENCES

Description: Most sensitive (0,088pmol/m) colorimetric kit for extracellular cGMP quantification.

UOM: 1 * 1 KIT

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Référence Produit: (ENZOADI900093)

Fournisseur: ENZO LIFE SCIENCES

Description: Highly sensitive ELISA, measuring DHEA in culture supernatants, plasma, serum, saliva, and urine from any species.

UOM: 1 * 1 KIT

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Fournisseur: ENZO LIFE SCIENCES

Description: Produced in <i>E. coli</i>. Human LC3-I is fused at the N-terminus to a His-tag.

Référence Produit: (ENZOADIAAP149E)

Fournisseur: ENZO LIFE SCIENCES

Description: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

UOM: 1 * 100 µG

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Fournisseur: ENZO LIFE SCIENCES

Description: Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation.

Fournisseur: ENZO LIFE SCIENCES

Description: Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin, MuSK and Rapsyn are all essential components for AChR aggregation through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface, and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa. The diagram shown indicates the domain structure and functional regions of agrin, as well as domains required for AChR aggregation and alpha-dystroglycan and heparin binding.  Various agrin isoforms are generated by alternative splicing at the X, Y and Z sites, and differ in the presence or absence of small inserts. The isoforms can determine the biological activity of agrin and their expression in specific tissues and stages of development. While no difference in functional activity has been detected between splicing variants at site X, insertion of a 4 aa peptide at site Y modestly increases agrins nAChR clustering activity. Insertion of an 8 aa peptide at splicing site Z increases the clustering activity of soluble rat agrin 10,000 fold.

Référence Produit: (ENZOADI9502310025)

Fournisseur: ENZO LIFE SCIENCES

Description: IHC universal negative control reagent is specifically designed to work with rabbit, mouse and goat antibodies.

UOM: 1 * 25 mL

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Référence Produit: (ENZOADI950010100)

Fournisseur: ENZO LIFE SCIENCES

Description: Fixation/Permeabilization, (buffer)

UOM: 1 * 100 mL

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Référence Produit: (ENZOADI920001)

Fournisseur: ENZO LIFE SCIENCES

Description: For the quantitative determination of PGE2 in culture supernatants from any species.

UOM: 1 * 100 Tests

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Référence Produit: (ENZOADI930001)

Fournisseur: ENZO LIFE SCIENCES

Description: Ultrasensitive PGE2 ELISA kit for inflammation and eicosanoid research.

UOM: 1 * 1 KIT

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Référence Produit: (ENZOADIKAMCC210E)

Fournisseur: ENZO LIFE SCIENCES

Description: DNA-topoisomerase II, also known as Topo II or Top 2, is a multifunctional nuclear enzyme required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities because of its ability to alter DNA supercoiling. In mammalian cells, Topo II consists of two isozymes, Topo II-alpha (170kDa) and Topo II-beta (180kDa) and expression and localization of each isoform are distinct and stage specific during the cell cycle. Topo II-beta is expressed constitutively throughout the cell cycle, whereas the expression of Topo II-alpha is cell cycle-regulated, peaking in G2 to M phase and declining to a minimal level at the end of M phase. DNA-topoisomerase II is the target of some of the most active drugs used in chemotherapy and has been shown to have a critical role in neural development.

UOM: 1 * 100 µG

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Référence Produit: (ENZOADIKAPGP006E)

Fournisseur: ENZO LIFE SCIENCES

Description: The Rab family of GTP-binding proteins are members of the Ras superfamily of small G proteins, and participate in multiple steps of the membrane trafficking. Rab3A participates in the fusion of synaptic vesicles during neurotransmitter release, a process regulated by GDP/GDP exchange cofactors such as GAP, GDI, GRF, and rabphilin. Rab4 regulates recycling of proteins from the early endosome to the surface of many cell types, regulating glucose transporter and transferrin receptor cell surface localization. Rab5 regulates the fusion of plasma membrane-derived clathrin-coated vesicles with early endosomes and homotypic fusion among early endosomes.

UOM: 1 * 100 µG

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Référence Produit: (ENZOADIKAPST206E)

Fournisseur: ENZO LIFE SCIENCES

Description: IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression.

UOM: 1 * 100 µG

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