Votre recherche pour: ENZO LIFE SCIENCES

Référence Produit: (ENZOBMLSA1130200)

Fournisseur: ENZO LIFE SCIENCES

Description: Host: Chicken

UOM: 1 * 200 µG

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Fournisseur: ENZO LIFE SCIENCES

Description: Oxido-squalene cyclase inhibitor

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Fournisseur: ENZO LIFE SCIENCES

Description: Host: Rabbit

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Référence Produit: (ENZOBMLS1080005)

Fournisseur: ENZO LIFE SCIENCES

Description: A potent and selective inhibitor of α-L-fucosidases.

UOM: 1 * 5 mg

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Référence Produit: (ENZOBMLS1090005)

Fournisseur: ENZO LIFE SCIENCES

Description: Potent inhibitor of α-mannosidase I. Blocks the biosynthesis of complex-type oligosaccharides. Does not inhibit the biosynthesis of lipid-linked oligosaccharides. Induces ER stress in human cells.

UOM: 1 * 5 mg

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Fournisseur: ENZO LIFE SCIENCES

Description: Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.

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Fournisseur: ENZO LIFE SCIENCES

Description: Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.

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Référence Produit: (ENZOBMLEI3940010)

Fournisseur: ENZO LIFE SCIENCES

Description: Cell permeable inhibitor of RhoA- and RhoC-mediated signaling. Inhibits LPA-induced DNA synthesis in PC-3 prostate cancer cell lines (<1µM) and inhibits the growth of RhoC-overexpressing melanoma cell lines (A375M2 and SK-Mel-147) at nanomolar concentrations.

UOM: 1 * 10 mg

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Référence Produit: (ENZOBMLEI3720001)

Fournisseur: ENZO LIFE SCIENCES

Description: A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenografted and allografted mice. Picropodophyllin downregulates IGF-1R by interfering with the action of β-arrestin 1/MDM2. It causes tumor regression and attenuates invasiveness of uveal melanoma cells. It displays beneficial effects on tumor growth, angiogenesis, bone disease and survival in a mouse multiple myeloma model. It attenuates intimal hyperplasia after vascular injury. Inhibition of IGF-1R is non-competitive with ATP.

UOM: 1 * 1 mg

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Référence Produit: (ENZOBMLEI3540001)

Fournisseur: ENZO LIFE SCIENCES

Description: Jnk inhibitor

UOM: 1 * 1 mg

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Référence Produit: (ENZOBMLEI3650010)

Fournisseur: ENZO LIFE SCIENCES

Description: A selective inhibitor of MEK1 and MEK2 (IC50= 0.18 and 0.22 µM respectively). Displays neuroprotective effects against ischemic brain injury.

UOM: 1 * 10 mg

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Fournisseur: ENZO LIFE SCIENCES

Description: Blocks actin filament assembly

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Fournisseur: ENZO LIFE SCIENCES

Description: HIF-1α activator.

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Référence Produit: (ENZOBMLGR3500025)

Fournisseur: ENZO LIFE SCIENCES

Description: HDAC inhibitor

UOM: 1 * 25 mg

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Référence Produit: (ENZOBMLGR3350025)

Fournisseur: ENZO LIFE SCIENCES

Description: Negative control for cyclopamine.

UOM: 1 * 25 mg

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Fournisseur: ENZO LIFE SCIENCES

Description: Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.

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