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Image Unavailable-BOSSBS-1037R-CY3

Anti-F2 Rabbit Polyclonal Antibody (Cy3®)

Référence Produit: (BOSSBS-1037R-CY3)
Fournisseur: Bioss
Description: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5758R-CY5.5

Anti-FAP Rabbit Polyclonal Antibody (Cy5.5®)

Référence Produit: (BOSSBS-5758R-CY5.5)
Fournisseur: Bioss
Description: In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.
UOM: 1 * 100 µl
Image Unavailable-GLCLSU780U-11P30-3

Accessoires pour congélateurs à ultra basse température Stirling

Référence Produit: (GLCLSU780U-11P30-3)
Fournisseur: Stirling Ultracold
Description: Étagères avec 12 clips de maintien, Pour: —
UOM: 1 * 3 Pce
Product Image-BWTEGA-BALERT

Accessories for gas alert extreme

Référence Produit: (BWTEGA-BALERT)
Fournisseur: BW TECHNOLOGIES
Description: Accessoires pour systèmes de détection de gaz, Pour: Extreme, Rubber boot wth stainless steel alligator clip
UOM: 1 * 1 Pce
Image Unavailable-BOSSBS-10118R-A647

Anti-MST1R Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-10118R-A647)
Fournisseur: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-CY5

Anti-VAV3 Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-4286R-CY5)
Fournisseur: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-A350

Anti-VAV3 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Référence Produit: (BOSSBS-4286R-A350)
Fournisseur: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3425R-A750

Anti-Smad3 Ser423 + Ser425 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Référence Produit: (BOSSBS-3425R-A750)
Fournisseur: Bioss
Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10118R-CY7

Anti-MST1R Rabbit Polyclonal Antibody (Cy7®)

Référence Produit: (BOSSBS-10118R-CY7)
Fournisseur: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0823R-CY5

Anti-GRN Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-0823R-CY5)
Fournisseur: Bioss
Description: Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
UOM: 1 * 100 µl
Image Unavailable-TENATE76120

Label holders, clip on, for freezer racks

Fournisseur: Tenak A/S
Description: These clip on label holders are ideal for easy organizing of freezers.

Product Image-METOL24WS

Shelf ledges, for solid shelving systems, Super Erecta®

Référence Produit: (METOL24WS)
Fournisseur: Metro International
Description: Shelf ledges for solid shelves. Sturdy ledges (101 mm) contain items on shelves. Spring-clip tabs included for attachment.
UOM: 1 * 1 Pce
Product Image-590-0346

Tapis antistatiques, b.safe

Référence Produit: (590-0346)
Fournisseur: Bohlender
Description: Tapis en matériau dissipateur d'électricité statique avec câble de mise à la terre monté en permanence, comprenant un clip pour la connexion à la terre.
UOM: 1 * 1 Pce
Product Image-WILMWG-6192

NMR tube carrier, SP Wilmad-LabGlass

Référence Produit: (WILMWG-6192)
Fournisseur: SP Industries
Description: Made from unbreakable polymer material with a snap-on cap, these tube carriers feature a shirt clip that keeps it secured in lab coat pockets.
UOM: 1 * 3 Pce
Image Unavailable-BOSSBS-0671R-CY5

Anti-DDR1 Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-0671R-CY5)
Fournisseur: Bioss
Description: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
UOM: 1 * 100 µl
Product Image-817-0058

VWR®, Rubans adhésifs pour salle blanche, usage général

Fournisseur: VWR Collection
Description: Ces rubans en vinyle adhésifs multi-usages enroulés autour d'un rouleau en plastique sont parfaits pour la maintenance des salles propres et l'utilisation dans les annexes.

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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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Veuillez noter qu'une autorisation peut être nécessaire pour commander ce produit. Un représentant de VWR vous contactera si votre commande le nécessite.
Ce produit a été bloqué par votre entreprise. Veuillez s'il vous plait contacter votre service achats pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Ce produit n'est plus disponible. Des alternatives peuvent être disponibles en faisant une recherche avec la référence VWR ci-dessus. Si vous avez besoin d'aide, s'il vous plaît appelez le Service Clients au 0825 02 30 30 (0,18 € TTC/mn).
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