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Product Image-PLUM5506

Plaster dispenser, QuickFix® Aloe Vera

Fournisseur: Plum Safety
Description: This plaster dispenser allows quick and hygienic first-aid access, at the centre of the workplace. Pull to retrieve a ready-for-use plaster, and get back to work in seconds.

Image Unavailable-BOSSBS-10118R-HRP

Anti-MST1R Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-10118R-HRP)
Fournisseur: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10118R-A488

Anti-MST1R Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Référence Produit: (BOSSBS-10118R-A488)
Fournisseur: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-CY5.5

Anti-VAV3 Rabbit Polyclonal Antibody (Cy5.5®)

Référence Produit: (BOSSBS-4286R-CY5.5)
Fournisseur: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-FITC

Anti-VAV3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-4286R-FITC)
Fournisseur: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-A750

Anti-VAV3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Référence Produit: (BOSSBS-4286R-A750)
Fournisseur: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organisation and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4286R-A647

Anti-VAV3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-4286R-A647)
Fournisseur: Bioss
Description: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5776R-HRP

Anti-PDGFD Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-5776R-HRP)
Fournisseur: Bioss
Description: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).
UOM: 1 * 100 µl
Product Image-201-7343

Pinces à fourches pour joints rodés

Fournisseur: Lenz Laborglas GmbH & CO.KG
Description: Clips pour joints sphériques, en acier inoxydable chrome/nickel.

Product Image-JSPAANX060-230-000

Visors and carriers for Evolution® safety helmets, Surefit™

Fournisseur: JSP
Description: Visor carrier clips into universal slot ear defender housing for the Evolution® safety helmet range. Available with polycarbonate or acetate visors to offer protection against high speed particles, liquid droplets and molten metal.

Product Image-PLUM5516

Plaster dispenser, QuickFix® blood stopper

Fournisseur: Plum Safety
Description: This plaster dispenser allows quick and hygienic first-aid access, at the centre of the workplace. Pull to retrieve a ready-for-use plaster, and get back to work in seconds.

Product Image-118-0235

Distributeur de pansements, QuickFix Elastic Long

Fournisseur: Plum Safety
Description: Distributeur de pansements élastiques en matériau respirant pour le bout des doigts. Les pansements peuvent être enroulés plusieurs fois autour du doigt. Le distributeur contient 60 pansements (2 recharges) et peut se fixer au mur.

Image Unavailable-BOSSBS-0671R-A750

Anti-MCK10 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Référence Produit: (BOSSBS-0671R-A750)
Fournisseur: Bioss
Description: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodelling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodelling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0671R-HRP

Anti-DDR1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-0671R-HRP)
Fournisseur: Bioss
Description: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
UOM: 1 * 100 µl
Product Image-118-0545

Distributeur de pansements QuickFix Elastic/ étanche

Référence Produit: (118-0545)
Fournisseur: Plum Safety
Description: Distributeur de pansements avec une combinaison de pansements résistants à l'eau et de pansements élastiques (45 de chaque). Le distributeur de pansements est adapté aux zones de travail normales et humides. Les pansements résistants à l'eau sont fabriqués en polyéthylène protecteur, doux pour la peau et respirant. Les pansements élastiques en tissu textile s'adaptent aux mouvements de la peau et sont donc confortables à porter.
UOM: 1 * 1 Pce
Image Unavailable-MMMA7100317692

3M™ Clear Reusable Polycon Earplug Storage Box

Référence Produit: (MMMA7100317692)
Fournisseur: 3M
Description: Robust reusable storage case to store 3M™ earplugs safely and securely. Case includes belt clip for convenient storage and easy access. Transparent colour allows for quick visual confirmation that the product is in the box.
UOM: 1 * 50 Pce
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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Le produit original n'est plus disponible. Le remplacement représenté est disponible
Ce produit n'est plus disponible. Des alternatives peuvent être disponibles en faisant une recherche avec la référence VWR ci-dessus. Si vous avez besoin d'aide, s'il vous plaît appelez le Service Clients au 0825 02 30 30 (0,18 € TTC/mn).
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