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Image Unavailable-BOSSBS-3055R-HRP

Anti-BTK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-3055R-HRP)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3069R-A680

Anti-BTK Tyr223 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-3069R-A680)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilisation, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defence. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3055R-A555

Anti-BTK Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-3055R-A555)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3055R-CY5.5

Anti-BTK Rabbit Polyclonal Antibody (Cy5.5®)

Référence Produit: (BOSSBS-3055R-CY5.5)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Product Image-1.09400.9010

Solutions tampon, Certipur®, avec codes couleur, Supelco®

Fournisseur: Merck
Description: Pour un étalonnage précis et une meilleure surveillance des pH-mètres.

FDS (Fiche de données de sécurité) Certificats. Environmentally Preferable

Product Image-391-2031

Plaque de contact, Sterilin®

Référence Produit: (391-2031)
Fournisseur: Sterilin
Description: Idéal pour la surveillance régulière de l'hygiène des surfaces.
UOM: 1 * 300 Pce
Image Unavailable-BOSSBS-3055R-A680

Anti-Btk Ser180 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-3055R-A680)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilisation, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defence. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Product Image-620-2486

VWR® Traceable®, Thermo-hygromètre à alarme à distance

Fournisseur: VWR Collection
Description: Ces thermo-hygromètres sont idéals pour les mesures de routine, la surveillance 24 heures sur 24, tous les besoins de contrôle qualité et les exigences expérimentales sensibles. Parfaits pour une utilisation dans les hottes, salles de classe, entrepôts, chambres pour tests environnementaux et zones de stockage de produits chimiques.

Product Image-135-2907

Kit d'accessoires Gateway pour l'activation OPC™ UA des armoires de sécurité biologique

Référence Produit: (135-2907)
Fournisseur: Thermo Scientific
Description: Permettez l'intégration de l'architecture unifiée de communication de plateforme ouverte (OPC™ UA) des postes de sécurité biologique Thermo Scientific™ à l'aide de ce kit d'accessoires de passerelle. Bénéficiez de tout le potentiel de l'intégration d'équipements de laboratoire dans vos nouveaux systèmes de contrôle distribués (DCS) ou ceux déjà en place, notamment la tenue de registres sans papier, la surveillance à distance, l'analyse dans le Cloud et plus encore.
UOM: 1 * 1 Pce
Product Image-621-0041

Accessories for buchi melting point apparatus M560 and M565

Fournisseur: BUCHI
Description: Logiciel de surveillance du point de fusion, Pour: Appareil à point de fusion M-565

Product Image-171-0874

Systèmes de purification de l'eau, PURELAB® Flex 3 et 4

Référence Produit: (171-0874)
Fournisseur: ELGA LabWater
Description: Le PURELAB® Flex est spécialement conçu pour répondre aux besoins de l'utilisateur. Il combine la facilité d'utilisation avec la distribution précise d'eau pure. Le distributeur manuel à utilisation intuitive est néanmoins sophistiqué et permet à l'utilisateur de distribuer de façon précise tout volume d'eau spécifique choisi, à la qualité exacte nécessaire. Surveillance intelligente en temps réel du carbone organique total (TOC). Choix unique d'options de distribution d'eau. Installation sur paillasse/murale. Produisez de l'eau OI de type III à partir d'eau prépurifiée ou d'eau du robinet.
UOM: 1 * 1 Pce
Product Image-620-2757

Instrument de contrôle du CO₂ pour surveiller la qualité de l'air intérieur (QAI)

Référence Produit: (620-2757)
Fournisseur: ROTRONIC INSTRUMENTS
Description: L'instrument à affichage de CO₂ peut être mural ou placé sur une paillasse, il évalue la qualité de l'air et mesure le CO₂, l'humidité et la température.
UOM: 1 * 1 Pce
Image Unavailable-BOSSBS-3055R-CY5

Anti-BTK Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-3055R-CY5)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3069R-FITC

Anti-BTK Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-3069R-FITC)
Fournisseur: Bioss
Description: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
UOM: 1 * 100 µl
Image Unavailable-1.09409.1000

Solutions tampons prêtes à l'emploi, Certipur®, Supelco®

Fournisseur: Merck
Description: Pour l'étalonnage précis et une meilleure surveillance des pH-mètres.

FDS (Fiche de données de sécurité) Certificats.

Product Image-431-0194

Homogénéiseur, POLYTRON®, PT 6100 D

Référence Produit: (431-0194)
Fournisseur: KINEMATICA
Description: Modèle autonome, plage de volumes 0,1 à 30 litres. Le puissant système PT 6100D a été conçu pour offrir des conditions d'homogénéisation reproductibles pour des volumes pouvant atteindre 30 litres, avec possibilité de sélectionner et modifier la vitesse et la durée de fonctionnement, tout en surveillant la température. L'unité peut être contrôlée via le clavier à membrane ou à partir d'un PC exécutant le logiciel KIN via une interface RS232.
UOM: 1 * 1 Pce
Prix sur demande
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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