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Image Unavailable-BOSSBS-11027R-CY7

Anti-KIF5A Rabbit Polyclonal Antibody (Cy7®)

Référence Produit: (BOSSBS-11027R-CY7)
Fournisseur: Bioss
Description: NKHC1 is a neuronal-specific component of a multi-subunit “molecular motor” complex that mediates intracellular organelle transport. Mutations in the gene encoding NKHC1 cause autosomal dominant spastic paraplegia 10. NKHC1 has a pan-neuronal distribution in the nervous system. Rat tissue extracts by immunoblot of NKHC1 can produce a doublet only in brain and sciatic nerve tissue. NKHC1 is distributed throughout the central nervous system and is enriched in subsets of neurons. Within cultured hippocampal neurons, NKHC1 is concentrated in the perinuclear region of the cell body. Kinesin superfamily proteins like NKHC1 are the molecular motors conveying cargos along microtubules.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11027R-FITC

Anti-KIF5A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-11027R-FITC)
Fournisseur: Bioss
Description: NKHC1 is a neuronal-specific component of a multi-subunit “molecular motor” complex that mediates intracellular organelle transport. Mutations in the gene encoding NKHC1 cause autosomal dominant spastic paraplegia 10. NKHC1 has a pan-neuronal distribution in the nervous system. Rat tissue extracts by immunoblot of NKHC1 can produce a doublet only in brain and sciatic nerve tissue. NKHC1 is distributed throughout the central nervous system and is enriched in subsets of neurons. Within cultured hippocampal neurons, NKHC1 is concentrated in the perinuclear region of the cell body. Kinesin superfamily proteins like NKHC1 are the molecular motors conveying cargos along microtubules.
UOM: 1 * 100 µl
Image Unavailable-71092-3

PopCulture® reagent

Fournisseur: Merck Millipore (Novagen)
Description: Le réactif PopCulture® est un concentré à base de détergent qui peut être ajouté directement aux cultures d'E. coli pour une extraction efficace des protéines sans récolte de cellules. Les protéines recombinantes peuvent être directement criblées dans l'extrait brut ou purifiées par l'ajout d'une matrice d'affinité, le lavage du complexe matrice-protéines cibles afin d'en éliminer le milieu de culture usagé et les contaminants cellulaires et l'élution des protéines purifiées de la matrice. La procédure de purification de protéines PopCulture convient parfaitement au traitement robotisé haut débit d'échantillons pour la recherche protéomique ou pour toute autre application pouvant bénéficier de l'accélération et du confort accru des procédures.

Product Image-PIER84850

Accessories for mass spectrometry sample preparation kit

Référence Produit: (PIER84850)
Fournisseur: Thermo Fisher Scientific
Description: Pierce™ C18 spin tips, for elution of up to 10 µg peptides per 20 µl sample for MS
UOM: 1 * 1 KIT
Image Unavailable-ENZOBMLKI1040050

Fluor-de-Lys® Deacetylase Substrate

Référence Produit: (ENZOBMLKI1040050)
Fournisseur: ENZO LIFE SCIENCES
Description: Fluor de Lys® Substrate is a highly sensitive and convenient alternative to radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. The Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.). Deacetylation of the substrate sensitizes the substrate so that, in a second step, treatment with the Fluor de Lys® Developer produces a fluorophore. Histone deacetylases from all known classes have been successfully assayed with the Fluor de Lys® Substrate. These include human HDACs 1, 2, 3 and 8 (class I), human HDACs 4 and 9 (class II) and the sirtuins yeast Sir2, human SIRT1 and human SIRT2 (class III; reaction must include the sirtuin substrate NAD+). The substrate is cell-permeable and serves as the basis for the HDAC Cellular Activity Assay Kit (Prod. No. BML-AK503). NOTE: Must be used in conjunction with Fluor de Lys® Developer (Prod. No. BML-KI105). Sufficient for 100-1000 assays of HDACs or sirtuins (50 µl reaction volume, 50-500 µM (substrate).
UOM: 1 * 50 µl
Product Image-PIER89801

Mitochondria isolation kit for tissue

Référence Produit: (PIER89801)
Fournisseur: Thermo Fisher Scientific
Description: The Mitochondria Isolation Kit for Tissue enables isolation of intact mitochondria from soft and hard tissue samples in about an hour.
UOM: 1 * 1 KIT
Product Image-PIER89875

Albumin/IgG removal kit, Pierce™

Référence Produit: (PIER89875)
Fournisseur: Thermo Fisher Scientific
Description: The Pierce™ Albumin/IgG Removal Kit is optimised to decrease the abundant albumin and antibody components of human serum samples in preparation for 2D electrophoresis and other protein profiling methods. By eliminating most of these two proteins, which account for nearly 70% of total serum proteins, other less abundant proteins of interest can be more easily detected and studied.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-9393R-A555

Anti-VPRBP Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-9393R-A555)
Fournisseur: Bioss
Description: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9393R-A488

Anti-VPRBP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Référence Produit: (BOSSBS-9393R-A488)
Fournisseur: Bioss
Description: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
UOM: 1 * 100 µl
Product Image-PIER87791

Subcellular protein fractionation kit for tissues

Fournisseur: Thermo Fisher Scientific
Description: This kit is ideal for cell fractionation and enrichment of proteins from five different cellular compartments within two hours.

Product Image-PIER20343

Immobilized pepsin, Pierce™

Référence Produit: (PIER20343)
Fournisseur: Thermo Fisher Scientific
Description: Immobilised Pepsin agarose consists of an acidic endopeptidase that has been immobilised onto beaded agarose resin to enable generation and purification of Fab and F(ab')2 fragments from antibodies.
UOM: 1 * 5 mL
Image Unavailable-PIER84868

High pH reversed-phase kit, Pierce™

Référence Produit: (PIER84868)
Fournisseur: Thermo Fisher Scientific
Description: Pierce™ High pH Reversed-Phase Kit increases protein identification from LC/MS analysis through orthogonal peptide fractionation of complex peptide samples.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-0559R-HRP

Anti-CDK5 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-0559R-HRP)
Fournisseur: Bioss
Description: CDK5 is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression.CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
UOM: 1 * 100 µl
Product Image-PIER90058

Trypsin protease, MS grade

Fournisseur: Thermo Fisher Scientific
Description: Pierce™ Trypsin Protease, MS Grade, is highly purified porcine trypsin that has been chemically modified for maximum activity and stability in proteomic applications.

Product Image-PIER87779

Pierce™ Detergent Removal Spin Columns and Resin

Fournisseur: Thermo Fisher Scientific
Description: Pierce™ Detergent removal resin enables removal of commonly used ionic, non-ionic and zwitterionic detergents from protein/peptide digest solutions.

Image Unavailable-BOSSBS-0092R-A555

Anti-CASP10 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-0092R-A555)
Fournisseur: Bioss
Description: Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.
UOM: 1 * 100 µl
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