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Référence Produit: (BOSSBS-13282R-CY5)
Fournisseur: Bioss
Description: May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
UOM: 1 * 100 µl


Fournisseur: ENZO LIFE SCIENCES
Description: Monomeric G-protein Ras functions as a molecular switch linking receptor and nonreceptor tyrosine kinase activation to a number of downstream signaling pathways. Oncogenic mutations, which occur in approximately 30% of all cases of human cancer, lead to the stimulation of proliferation and the inhibition of apoptosis.

Référence Produit: (BOSSBS-3872R-A555)
Fournisseur: Bioss
Description: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-11204R-A680)
Fournisseur: Bioss
Description: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-3872R-CY5.5)
Fournisseur: Bioss
Description: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl


Fournisseur: Molecular Devices
Description: Le lecteur de microplaques SpectraMax® L mesure les tests de luminescence flash et glow dans des plaques à 96 et 384 puits.

Référence Produit: (BOSSBS-3872R-A750)
Fournisseur: Bioss
Description: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-5708R-CY5)
Fournisseur: Bioss
Description: SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
UOM: 1 * 100 µl


Fournisseur: Brady
Description: Ces dispositifs miniatures de condamnation par câble sont parfaitement adaptés aux interrupteurs d'isolement, aux petits robinets-vannes, etc.

Référence Produit: (BOSSBS-1286R-CY3)
Fournisseur: Bioss
Description: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-5708R-A350)
Fournisseur: Bioss
Description: SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
UOM: 1 * 100 µl


Fournisseur: VWR Collection
Description: Remote temperature probes for circulator use with a chiller. Allows points of control to be switched from inside a chiller to a remote location. Compensates for heat loss through tubing between the circulator and the control point. Platinum RTD sensor with stainless steel sheath. Rubber coupling with 25,4 mm Ø, connects sheath to flexible cable. Probe cable ends in a DB9 female plug.

Référence Produit: (BOSSBS-9526R-FITC)
Fournisseur: Bioss
Description: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity).
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-9526R-A555)
Fournisseur: Bioss
Description: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity).
UOM: 1 * 100 µl


Référence Produit: (USBIS8875-01H)
Fournisseur: US Biological
Description: Anti-SWAP-70 Goat Polyclonal Antibody
UOM: 1 * 100 µG


Référence Produit: (BOSSBS-1286R-FITC)
Fournisseur: Bioss
Description: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
UOM: 1 * 100 µl


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