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Référence Produit: (BOSSBS-3843R-A488)
Fournisseur: Bioss
Description: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].
UOM: 1 * 100 µl


Fournisseur: Avantor
Description: Convient pour une utilisation sur les instruments Dynex DSX et DS2. Disponible en version non conductrice, sans filtre, en rack conteneur et en version marquée CE-IVD pour les applications de diagnostic clinique.

Environmentally Preferable

Référence Produit: (BOSSBS-4105R-HRP)
Fournisseur: Bioss
Description: Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-4278R-A488)
Fournisseur: Bioss
Description: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-1393R-CY5.5)
Fournisseur: Bioss
Description: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-8053R)
Fournisseur: Bioss
Description: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-8053R-CY5.5)
Fournisseur: Bioss
Description: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
UOM: 1 * 100 µl


Fournisseur: VWR Collection
Description: En PS, forme hexagonale.

Référence Produit: (521-2853)
Fournisseur: VWR Collection
Description: La centrifugeuse CompactStar CS4 est conçue pour séparer les échantillons dans les domaines de la chimie, les sciences de la vie, la recherche clinique et le diagnostic.
UOM: 1 * 1 Pce


Fournisseur: Bertin Instruments
Description: Cônes stériles, usage unique, PC

Fournisseur: VWR Collection
Description: Fabriqués à partir d'un maillage en nylon solide avec des pores de maille régulièrement espacés, ces passoires cellulaires sont des dispositifs stériles et faciles à utiliser pour isoler rapidement les cellules primaires afin d'obtenir de manière constante une suspension unicellulaire uniforme à partir des tissus. Conçu pour protéger les précieux instruments de cytométrie en flux et de tri cellulaire en éliminant de manière fiable les amas et les débris des suspensions cellulaires et des échantillons cliniques avant l'analyse.
Référence Produit: (BOSSBS-3843R-CY7)
Fournisseur: Bioss
Description: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].
UOM: 1 * 100 µl


Fournisseur: HIRSCHMANN
Description: Capillaires à usage unique pour la centrifugation des analyses de sang.

Référence Produit: (BOSSBS-1393R-FITC)
Fournisseur: Bioss
Description: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
UOM: 1 * 100 µl


Fournisseur: Thermo Fisher Scientific
Description: Polycarbonate, clear.

Environmentally Preferable

Fournisseur: HARTMANN PAUL
Description: These single-use surgical gowns made of a multilayer, fluid repellent, non woven fabric provide great resistance against the penetration of fluids and bacteria.

Prix sur demande
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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Ce produit n'est plus disponible. Des alternatives peuvent être disponibles en faisant une recherche avec la référence VWR ci-dessus. Si vous avez besoin d'aide, s'il vous plaît appelez le Service Clients au 0825 02 30 30 (0,18 € TTC/mn).
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