Disposable, multipurpose in-line filters are designed for the purpose of small-volume venting of solvents and for gas filtration. PTFE membrane and polypropylene housing have broad chemical compatibility. In-line filters can be used to help protect against bloodborne pathogens. They are useful for benchtop fermentors, in-line gas filtration for sterile air or CO2, and protection of vacuum pumps from damage by aqueous solutions. These filters are autoclavable for easy cleaning.