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Image Unavailable-BOSSBS-1258R-CY3

Anti-ICAM2 Rabbit Polyclonal Antibody (Cy3®)

Description: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Référence Produit: BOSSBS-1258R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-903-0534

Accessoires pour VWR® Système HPLC Hitachi Chromaster

Description: Kit de montage de valve HPLC Chromaster
Référence Produit: 903-0534
UOM: 1 * 1 Pce
Fournisseur: VWR Collection
Image Unavailable-BOSSBS-15430R-CY3

Anti-HCST Rabbit Polyclonal Antibody (Cy3)

Description: Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilisation and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
Référence Produit: BOSSBS-15430R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-BUCH037133

Four de séchage en verre, B-585TO

Description: Petit four de séchage dans un boîtier métallique et une plate-forme robuste, la chambre de séchage étant toujours en verre pour une meilleure surveillance de l'échantillon. Il permet de sécher des résidus de solvants jusqu'à une température maxi de 300 °C.
Référence Produit: BUCH037133
UOM: 1 * 1 Pce
Fournisseur: BUCHI
Image Unavailable-BOSSBS-2566R-A350

Anti-CLEC6A Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Dectin 2 is a type II transmembrane protein that is a member of the C type lectin superfamily. In mouse, dectin 2 is predominantly expressed on tissue macrophages and some dendritic cells. Significant expression of Dectin 2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin 2 but transient up regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin 2 has not been fully determined but studies suggest a possible role in immune surveillance.
Référence Produit: BOSSBS-2566R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-15430R-A680

Anti-HCST Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Description: Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilisation and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
Référence Produit: BOSSBS-15430R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-15430R-A647

Anti-HCST Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Description: Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilisation and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
Référence Produit: BOSSBS-15430R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1258R-A680

Anti-ICAM-2/CD102 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Référence Produit: BOSSBS-1258R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1258R-FITC

Anti-ICAM2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Référence Produit: BOSSBS-1258R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-620-2277

VWR® Traceable®, Thermo-hygromètre numérique avec point de rosée

Description: Compteur pratique à triple lecture avec fonction « toujours allumé » pour surveiller en permanence les conditions. L'alarme sonore et LED peut être réglée pour se déclencher à trois lectures d'humidité différentes (55 %, 60 % ou 65 %). Les capteurs offrent des temps de réponse en moins de 30 secondes.
Référence Produit: 620-2277
UOM: 1 * 1 Pce
Fournisseur: VWR Collection
Image Unavailable-BNC471054-100

Anti-HLA-A; HLA-B; HLA-C Mouse Monoclonal Antibody (CF647) [clone: 246-B8.E7]

Description: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Référence Produit: BNC471054-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Image Unavailable-BNC401054-500

Anti-HLA-A; HLA-B; HLA-C Mouse Monoclonal Antibody (CF640R) [clone: 246-B8.E7]

Description: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Référence Produit: BNC401054-500
UOM: 1 * 500 µl
Fournisseur: Biotium
Image Unavailable-BNUB1054-100

Anti-HLA-A; HLA-B; HLA-C Mouse Monoclonal Antibody (Purified) [clone: 246-B8.E7]

Description: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Référence Produit: BNUB1054-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Image Unavailable-BOSSBS-15430R-A750

Anti-HCST Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Description: Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilisation and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
Référence Produit: BOSSBS-15430R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-730-1469

VWR® Imager2Imager CHEMI Premium, Systèmes de documentation de gel

Description: Les systèmes de documentation et d’analyse de gel VWR® Imager sont disponibles dans des configurations adaptées aux applications de fluorescence et de chimiluminescence. Les deux modèles sont équipés d’une caméra CCD numérique (3,8 ou 4 mégapixels) utilisant la dernière technologie USB. Le système standard comprend une caméra CCD 12 bits qui peut être modifiée en 16 bits par logiciel. Le système CHEMI Premium est équipé d’une véritable caméra CCD refroidie avancée 16 bits capable de capturer des images d’une large gamme d’échantillons chimiluminescents à l’aide de substrats courants.
Référence Produit: 730-1469
UOM: 1 * 1 Pce
Fournisseur: VWR Collection
Image Unavailable-BOSSBS-15430R-CY7

Anti-HCST Rabbit Polyclonal Antibody (Cy7)

Description: Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilisation and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
Référence Produit: BOSSBS-15430R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
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