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Description: Donkey anti-Rabbit IgG (H&L) - Affinity Pure, HRP Conjugate

Référence Produit: 72-8087-M001

UOM: 1 * 1 mg

Fournisseur: Tonbo Biosciences

*Promo

Description: Goat anti-Rabbit IgG (H&L) - Affinity Pure, HRP Conjugate

Référence Produit: 72-8067-M001

UOM: 1 * 1 mg

Fournisseur: Tonbo Biosciences

*Promo

Description: Sheep anti-Rabbit IgG (H&L) - Affinity Pure, FITC Conjugate

Référence Produit: 35-8078-M002

UOM: 1 * 2 mg

Fournisseur: Tonbo Biosciences

*Promo

Description: Rabbit anti-mouse IgG (H&L) - Affinity Pure, min x w/human serum proteins

Référence Produit: 70-8077-M002

UOM: 1 * 2 mg

Fournisseur: Tonbo Biosciences

*Promo

Description: Rabbit anti-Human IgM (mu chain) - Affinity Pure, FITC Conjugate

Référence Produit: 35-8075-M001

UOM: 1 * 1 mg

Fournisseur: Tonbo Biosciences

*Promo

Description: The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.

Référence Produit: 65-0047-T100

UOM: 1 * 100 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165 to 170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Référence Produit: 40-0112-U100

UOM: 1 * 100 µG

Fournisseur: Tonbo Biosciences

*Promo

Description: The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.

Référence Produit: 40-7102-U500

UOM: 1 * 500 µG

Fournisseur: Tonbo Biosciences

*Promo

Description: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Référence Produit: 35-0036-T100

UOM: 1 * 100 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.

Référence Produit: 80-4724-U100

UOM: 1 * 100 µG

Fournisseur: Tonbo Biosciences

*Promo

Description: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Référence Produit: 67-0036-T500

UOM: 1 * 500 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Référence Produit: 60-0036-T025

UOM: 1 * 25 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.

Référence Produit: 20-0564-T100

UOM: 1 * 100 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.

Référence Produit: 20-0237-T500

UOM: 1 * 500 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The L17F12 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is a member of the scavenger receptor superfamily and is present on approximately 70% of normal peripheral blood lymphocytes. CD5 is involved in modulating antigen receptor signaling in both T and B cells and acts through binding of CD72, its receptor expressed on B cells.

Référence Produit: 65-0058-T100

UOM: 1 * 100 Tests

Fournisseur: Tonbo Biosciences

*Promo

Description: The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation.

Référence Produit: 20-0209-T500

UOM: 1 * 500 Tests

Fournisseur: Tonbo Biosciences

*Promo