Votre recherche pour: STEMCELL Technologies

Fournisseur: STEMCELL Technologies

Description: Immunodensity depletion of lineage positive cells from cord blood.

Référence Produit: (STMC04236)

Fournisseur: STEMCELL Technologies

Description: Serum-free methylcellulose-based medium without cytokines for human cells.

UOM: 1 * 80 mL

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Référence Produit: (STMC36350)

Fournisseur: STEMCELL Technologies

Description: McCoy's 5A medium.

UOM: 1 * 500 mL

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Référence Produit: (STMC03234)

Fournisseur: STEMCELL Technologies

Description: Methylcellulose-based medium without cytokines (including EPO) for mouse cells.

UOM: 1 * 80 mL

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Référence Produit: (STMC36150)

Fournisseur: STEMCELL Technologies

Description: Iscove's Modified Dulbecco's Medium (IMDM) with 25 mm HEPES.

UOM: 1 * 500 mL

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Référence Produit: (STMC36250)

Fournisseur: STEMCELL Technologies

Description: Dulbecco's Modified Eagle's Medium (DMEM) with 4500 mg/l D-glucose.

UOM: 1 * 500 mL

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Référence Produit: (STMC05750)

Fournisseur: STEMCELL Technologies

Description: Basal medium for expansion of human neural stem and progenitor cells.

UOM: 1 * 450 mL

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Fournisseur: STEMCELL Technologies

Description: Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma <i>et al.</i>). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau <i>et al.</i>). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).

Fournisseur: STEMCELL Technologies

Description: Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf andamp; Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit <i>et al.</i>), the activation of metalloproteases that cleave VCAM-1 (Levesque <i>et al.</i>), and the release of norepinephrine from the sympathetic nervous system (Katayama <i>et al.</i>), leading to the release or mobilisation of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.

Référence Produit: (STMC04435)

Fournisseur: STEMCELL Technologies

Description: Methylcellulose-based medium with recombinant cytokines for human cells. 1x100ml bottle.

UOM: 1 * 100 mL

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Fournisseur: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human CD34, Alexa Fluor® 488-conjugated.

Fournisseur: STEMCELL Technologies

Description: Rat monoclonal IgG2b antibody against mouse Gr-1 (Ly-6G/Ly-6C), PE-conjugated.

Référence Produit: (STMC60063PE.1)

Fournisseur: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human SSEA-5, PE-conjugated.

UOM: 1 * 25 Tests

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Fournisseur: STEMCELL Technologies

Description: Immunomagnetic positive selection of mouse CD11c+ cells (e.g. dendritic cells (DC)) from mouse splenocytes or other tissues

Fournisseur: STEMCELL Technologies

Description: Immunomagnetic isolation of untouched rat CD4+ T cells

Référence Produit: (STMC60024AZ)

Fournisseur: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against mouse, rat, guinea pig CD90/CD90.1, APC-conjugated.

UOM: 1 * 100 µG

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