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Référence Produit: (59004.)
Fournisseur: Biotium
Description: Ready-to-use solution of Pluronic® F-127, a nonionic detergent useful for solubilizing hydrophobic dye molecules such as cell-permeable AM esters of Fura-2, Fluo-3, Indo-1, or Rhod-2 calcium indicators to facilitate cell loading.
UOM: 1 * 1 mL

Référence Produit: (NOVUNB110-12179)
Fournisseur: Novus Biologicals
Description: Mouse Monoclonal Complement C5 Antibody (557). Tested Applications: Western Blot, Blocking/Neutralizing, ELISA, Functional. Tested Reactivity: Human.
UOM: 1 * 50 µG


Fournisseur: ENZO LIFE SCIENCES
Description: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

Référence Produit: (AXYGI-4010)
Fournisseur: Corning
Description: Compact benchtop shaking incubator ideal for molecular biology applications. Uniformly heat, cool and shake samples within microtubes or microplates on demand. Requires no tools for block exchange via magnetic connection technology. Programmable up to six steps per nine programs. Can be used in a cold room environment.
UOM: 1 * 1 Pce

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Référence Produit: (BOSSBS-6385R-CY7)
Fournisseur: Bioss
Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
UOM: 1 * 100 µl


Référence Produit: (BNUM0643-50)
Fournisseur: Biotium
Description: This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF alpha induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin.
UOM: 1 * 50 µl


Référence Produit: (BOSSBS-5903R)
Fournisseur: Bioss
Description: Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
UOM: 1 * 100 µl


Référence Produit: (ENZOBMLPI1130005)
Fournisseur: ENZO LIFE SCIENCES
Description: Inhibits the metalloprotease neprilysin (neutral endopeptidase 24.11) and neprilysin 2. Inhibits opioid-degrading enzymes, potentiating THC-induced antinociception. Potentiates the effects of natriuretic peptides. Blocks enzymatic degradation of luteinizing hormone releasing hormone (LHRH).
UOM: 1 * 5 mg


Référence Produit: (391-0641)
Fournisseur: VWR Collection
Description: Pre-cut aluminum foil seals on a roll for PCR applications. Supplied on a roll with holder for ease of use.
UOM: 1 * 500 Pce


Référence Produit: (ENZOBMLEI3600005)
Fournisseur: ENZO LIFE SCIENCES
Description: PD-98059 is a potent and selective inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK thereby inhibiting the phosphorylation and the activation of MAP kinase. PD-98059 is cell permeable. In PC12 pheochromocytoma cells, it completely blocked the increase in MAP kinase activity produced by NGF, IC50=2µM. Enhances self-renewal of embryonic stem cells PD-98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Inhibits cell growth and proliferation in acute myelogenous leukemia cell lines by causing cell arrest.
UOM: 1 * 5 mg


Référence Produit: (BOSSBS-14082R-A750)
Fournisseur: Bioss
Description: Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
UOM: 1 * 100 µl


Référence Produit: (1B1509-25G)
Fournisseur: VWR Chemicals
Description: DNA, salt, from fish sperm is an effective blocking agent used to increase signal-to-noise ratio for detection during hybridisation.
UOM: 1 * 25 g

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Référence Produit: (BOSSBS-6385R-HRP)
Fournisseur: Bioss
Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-8177R-CY3)
Fournisseur: Bioss
Description: Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.
UOM: 1 * 100 µl


Fournisseur: Cayman Chemical
Description: A synthetic peptide corresponding to the nuclear localisation sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

Référence Produit: (BOSSBS-0738R-A750)
Fournisseur: Bioss
Description: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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Ce produit n'est plus disponible. Des alternatives peuvent être disponibles en faisant une recherche avec la référence VWR ci-dessus. Si vous avez besoin d'aide, s'il vous plaît appelez le Service Clients au 0825 02 30 30 (0,18 € TTC/mn).
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