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Image Unavailable-BOSSBS-6385R-FITC

Anti-GAS1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Référence Produit: BOSSBS-6385R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6385R-A350

Anti-GAS1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Référence Produit: BOSSBS-6385R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4029R-CY5

Anti-CA9 Rabbit Polyclonal Antibody (Cy5®)

Description: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Référence Produit: BOSSBS-4029R-CY5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4029R-A555

Anti-CA9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Référence Produit: BOSSBS-4029R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-3846R-CY3

Anti-TGFB5/ TGFB1 Rabbit Polyclonal Antibody (Cy3®)

Description: Transforming Growth Factor beta 5 (TGF beta 5) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.
Référence Produit: BOSSBS-3846R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-ENZOALX8049070100

Anti-TNF-related Apoptosis-inducing Ligand Mouse Monoclonal Antibody [clone: RIK-2]

Description: Induces apoptosis in tumorigenic and transformed cell lines, involved in T cell mediated cytotoxicity, TRAIL ligand of cognate receptors induces NF-kappa-B signaling in a variety of cell types. TRAIL is a 30kDa protein known as TNF-related apoptosis inducing ligand, CD253, TNFSF10, or Apo-2L. It can be expressed as a cell surface (30kDa) and soluble ligand (19-20kDa) produced by megakaryocytes and platelets, monocytes, neutrophils, NK cells and activated T cells. This antigen is also expressed on tumor cells and transformed cell lines. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. This antibody is useful for flow cytometric staining and blocking studies.
Référence Produit: ENZOALX8049070100
UOM: 1 * 100 µG
Fournisseur: ENZO LIFE SCIENCES
Product Image-EDVO300

Kits d'expérimentation, clonage bleu/blanc d'un fragment d'ADN et dosage de la ß-galactosidase

Description: When DNA is subcloned in the pUC polylinker region, β-galactosidase production is interrupted, resulting in the inability of cells to hydrolyse X-Gal. This results in the production of white colonies amongst a background of blue colonies. This experiment provides a DNA fragment together with a linear plasmid and T4 DNA ligase. Following the ligation to synthesis the recombinant plasmid, competent <i>E. coli</i> cells are transformed and the number of recombinant antibiotic-resistant white and blue colonies are counted. β-galactosidase activity is assayed from blue and white bacterial cells.
Référence Produit: EDVO300
UOM: 1 * 1 KIT
Fournisseur: EDVOTEK
Image Unavailable-BOSSBS-3846R-A555

Anti-TGFB5/ TGFB1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Transforming Growth Factor beta 5 (TGF beta 5) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.
Référence Produit: BOSSBS-3846R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-3846R-CY5.5

Anti-TGFB5/ TGFB1 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Transforming Growth Factor beta 5 (TGF beta 5) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.
Référence Produit: BOSSBS-3846R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-3846R-A680

Anti-TGF beta 5/ TGF beta 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Transforming Growth Factor beta 5 (TGF beta 5) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.
Référence Produit: BOSSBS-3846R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6136R-A350

Anti-AdV 5 E1A Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
Référence Produit: BOSSBS-6136R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6136R-A750

Anti-Adenovirus 5 E1A Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localised within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalisation of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
Référence Produit: BOSSBS-6136R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-392-0424

VWR®, Cell culture media, Minimum Essential Medium (MEM)

Description: Minimum Essential Medium (MEM) with Earle’s Balanced Salts is a modification of Eagle’s earlier Basal Medium (BME) which contains a higher concentration of essential nutrients. These media promote the growth of a variety of normal and transformed cells. Since they contain Earle’s Balanced Salts, they are suitable for use in atmospheres charged with CO₂ gas.
Référence Produit: 392-0424
UOM: 1 * 500 mL
Fournisseur: VWR Chemicals

FDS (Fiche de données de sécurité) Certificats.


Image Unavailable-BOSSBS-1684R-CY3

Anti-SKI Rabbit Polyclonal Antibody (Cy3®)

Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
Référence Produit: BOSSBS-1684R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1684R-A350

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
Référence Produit: BOSSBS-1684R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1719R-FITC

Anti-HPV16 E6 + HPV18 E6 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation.
Référence Produit: BOSSBS-1719R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
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