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Image Unavailable-BNC881119-100

Anti-TGFA Mouse Monoclonal Antibody (CF488A) [clone: TGFA/1119]

Description: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Référence Produit: BNC881119-100
UOM: 1 * 100 µl
Fournisseur: Biotium
Product Image-USBI038003

Anti-LTBP1 Rabbit Polyclonal Antibody

Description: Anti-LTBP1 Rabbit Polyclonal Antibody
Référence Produit: USBI038003
UOM: 1 * 200 µl
Fournisseur: US Biological
Image Unavailable-BOSSBS-3158R-A555

Anti-FOSL1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq].
Référence Produit: BOSSBS-3158R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-11457R-A555

Anti-S1PR5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Référence Produit: BOSSBS-11457R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6083R-A647

Anti-ANP32A Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
Référence Produit: BOSSBS-6083R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6083R-A750

Anti-PHAP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
Référence Produit: BOSSBS-6083R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6628R

Anti-ZDHHC17 Rabbit Polyclonal Antibody

Description: ZDHHC17 is a neuronal palmitoyl transferase. Palmitoylation is critical for trafficking and function of signaling molecules, neurotransmitter receptors, and synaptic scaffolding proteins in neurons.ZDHHC17 causes cellular transformation. It has been shown that mRNA encoding ZDHHC17 is up-regulated in a number of types of human tumors, thus ZDHHC17 and other PATs (palmitoyl acyltransferases) are potential targets for new anticancer drugs.
Référence Produit: BOSSBS-6628R
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-7000R

Anti-CTNND1 Rabbit Polyclonal Antibody

Description: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Référence Produit: BOSSBS-7000R
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BNUB0787-500

Anti-TGFA Mouse Monoclonal Antibody (Purified) [clone: P/T1]

Description: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Référence Produit: BNUB0787-500
UOM: 1 * 500 µl
Fournisseur: Biotium
Image Unavailable-BOSSBS-12993R-CY7

Anti-CTNND1 Rabbit Polyclonal Antibody (Cy7®)

Description: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Référence Produit: BOSSBS-12993R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-0673R-HRP

Anti-VTCN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation (By similarity).
Référence Produit: BOSSBS-0673R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1684R-CY5

Anti-SKI Rabbit Polyclonal Antibody (Cy5®)

Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
Référence Produit: BOSSBS-1684R-CY5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1684R-HRP

Anti-SKI Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
Référence Produit: BOSSBS-1684R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-2969R-A350

Anti-HPV33 E7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
Référence Produit: BOSSBS-2969R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-2969R-A488

Anti-HPV33 E7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
Référence Produit: BOSSBS-2969R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-2969R-CY5.5

Anti-HPV33 E7 Rabbit Polyclonal Antibody (Cy5.5®)

Description: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
Référence Produit: BOSSBS-2969R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
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