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Image Unavailable-BOSSBS-6874R-CY5.5

Anti-CAT Rabbit Polyclonal Antibody (Cy5.5®)

Référence Produit: (BOSSBS-6874R-CY5.5)
Fournisseur: Bioss
Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13115R-A680

Anti-ETV6/Tel Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-13115R-A680)
Fournisseur: Bioss
Description: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6385R-CY7

Anti-GAS1 Rabbit Polyclonal Antibody (Cy7®)

Référence Produit: (BOSSBS-6385R-CY7)
Fournisseur: Bioss
Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
UOM: 1 * 100 µl
Image Unavailable-USBIT8250-50H

Anti-TGFBR3 Rabbit Polyclonal Antibody

Référence Produit: (USBIT8250-50H)
Fournisseur: US Biological
Description: Anti-TGFBR3 Rabbit Polyclonal Antibody
UOM: 1 * 50 µG
Product Image-BSENC-1541-100

Anti-TGF-1 Chicken Polyclonal Antibody

Référence Produit: (BSENC-1541-100)
Fournisseur: Biosensis
Description: Transforming growth factor beta-1 (TGFB1) is a multi-functional cytokine with roles in proliferation, differentiation and other functions in many cell types. The secreted TGFB1 protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide (Ref: SWISS-Prot).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0100R-A488

Anti-TGFB2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Référence Produit: (BOSSBS-0100R-A488)
Fournisseur: Bioss
Description: Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0100R-CY5

Anti-TGFB2 Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-0100R-CY5)
Fournisseur: Bioss
Description: Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3738R-A647

Anti-CRKL Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-3738R-A647)
Fournisseur: Bioss
Description: Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3738R-A680

Anti-CrklTyr251 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-3738R-A680)
Fournisseur: Bioss
Description: Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6818R-HRP

Anti-MAGEA12 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-6818R-HRP)
Fournisseur: Bioss
Description: Not known, though may play a role in tumor transformation or aspects of tumor progression.Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6874R-FITC

Anti-CAT Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-6874R-FITC)
Fournisseur: Bioss
Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6874R-HRP

Anti-CAT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-6874R-HRP)
Fournisseur: Bioss
Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6874R-A647

Anti-CAT Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-6874R-A647)
Fournisseur: Bioss
Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0817R-CY3

Anti-MAGEA1 Rabbit Polyclonal Antibody (Cy3®)

Référence Produit: (BOSSBS-0817R-CY3)
Fournisseur: Bioss
Description: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2763R-A488

Anti-CRK Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Référence Produit: (BOSSBS-2763R-A488)
Fournisseur: Bioss
Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2763R-CY5.5

Anti-CRK Rabbit Polyclonal Antibody (Cy5.5®)

Référence Produit: (BOSSBS-2763R-CY5.5)
Fournisseur: Bioss
Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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