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Référence Produit: (PRSI79-526)
Fournisseur: ProSci Inc.
Description: Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-κB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition, progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.
UOM: 1 * 100 µG


Référence Produit: (466-0457)
Fournisseur: VWR Collection
Description: VWR®, Accessories for DRY-Line, VENTI-Line and INCU-Line Prime
UOM: 1 * 1 Pce


Référence Produit: (PERCN9300174)
Fournisseur: PerkinElmer
Description: Standard de mercure, Praseodyme 1.000 mg/l dans acide nitrique dilué (de Pr₆O₁₁) standard for AAS and ICP, 1000 mg/L, Mercure, Matrice: 10% HNO₃, Applications: Étalons ICP
UOM: 1 * 125 mL

Fournisseur: ACTIVE MOTIF
Description: Standard de praséodyme, Praseodyme 1.000 mg/l dans acide nitrique dilué étalon mono-élément pour ICP, 1000 mg/L, Praséodyme, Matrice: 2% HNO₃, Applications: Étalons ICP

Référence Produit: (PRSI33-250)
Fournisseur: ProSci Inc.
Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.
UOM: 1 * 100 µG

New Product


Référence Produit: (PRSI34-145)
Fournisseur: ProSci Inc.
Description: Cytokeratin 17 (CK17) is a member of the Cytokeratin subfamily of intermediate filament proteins (IF's). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. CK17 is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered an epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 can be useful when included in a panel of antibodies against TTF-1, napsin A, CK5&6, p63, and SOX-2 for diagnostic differentiation between lung adenocarcinoma (LADC) and lung squamous cell carcinoma (SCLC), especially for poorly-differentiated lung carcinoma. CK17 is expressed in SCLC much higher than in LADC. In breast carcinomas, approximately 20% of patients show no expression of ER, PR and Her2, which are defined as triple negative tumor. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
UOM: 1 * 100 µG

New Product


Référence Produit: (NABE691600507)
Fournisseur: NABERTHERM
Description: Accessories for muffle furnaces, L 1/11-L 40/12 and LE 1/11 - LE 14/11
UOM: 1 * 1 Pce


Fournisseur: IKA
Description: Orbital Shaker, Support universel AS 130.1. L×P×H 325×234×88 mm

Fournisseur: HIRSCHMANN
Description: DURAN®, verre borosilicaté, héparinées au sodium, à usage unique.

Fournisseur: Tenak A/S
Description: Stainless steel standard microplate racks.

Référence Produit: (115-0370)
Fournisseur: CONTEC
Description: Sontara AC is a white non woven creped wipe made with 55% special cellulose and 45% polyester.
UOM: 1 * 250 Pce


Fournisseur: IKA
Description: Orbital Shaker, Plateau à rouleaux, Lxpxh 480x500x120 mm

Fournisseur: Tenak A/S
Description: This is a complete range of racks for microtiterplates for use in chest freezers.

Fournisseur: Tenak A/S
Description: These microplate racks, made of aluminium, can be used for all freezer models.

Fournisseur: Tenak A/S
Description: Microplate racks, made of aluminium, can be used for all freezer models.

Fournisseur: Dräger
Description: Accessories for airflow indicator

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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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Ce produit n'est plus disponible. Des alternatives peuvent être disponibles en faisant une recherche avec la référence VWR ci-dessus. Si vous avez besoin d'aide, s'il vous plaît appelez le Service Clients au 0825 02 30 30 (0,18 € TTC/mn).
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