Votre recherche pour: Enzymes

Fournisseur: US Biological

Description: Cellulase (Onozuka R-10) is a multi-component enzyme system derived from <i>Trichoderma viride</i> and contains cellulase, alpha-amylase, hemicellulase, pectinase and protease activities.

Référence Produit: (J60093.MB)

Fournisseur: Thermo Fisher Scientific

Description: Elastase substrate V

UOM: 1 * 25 mg

FDS (Fiche de données de sécurité) Certificats. *Promo

Référence Produit: (PRSI91-408)

Fournisseur: ProSci Inc.

Description: Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI92-055)

Fournisseur: ProSci Inc.

Description: Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyses the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI92-618)

Fournisseur: ProSci Inc.

Description: Messenger RNA (mRNA) degradation plays a key role in the control of gene expression in all organisms by limiting the number of times that each mRNA molecule can be used as a template for protein synthesis. RNA pyrophosphohydrolase, also called RppH, is a master regulator of 5'-dependent mRNA decay. It accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. RppH preferentially hydrolyses diadenosine penta-phosphate with ATP as one of the reaction products, and can be able to hydrolyse diadenosine hexa- and tetra-phosphate. However, this protein has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In the meningitis causing strain<i> E. coli</i> K1, it has been shown to play a role in HBMEC (human brain microvascular endothelial cells) invasion <i>in vitro</i>.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI91-989)

Fournisseur: ProSci Inc.

Description: Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyses the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Defects in ITPase is thought to be inherited and is characterised by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI90-365)

Fournisseur: ProSci Inc.

Description: NAD kinase catalyses the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from <i>Mycobacterium tuberculosis</i> is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI92-523)

Fournisseur: ProSci Inc.

Description: Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyse reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumours and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI90-366)

Fournisseur: ProSci Inc.

Description: NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalysing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H₂O = AMP + diphosphate + NAD+ + L-glutamate.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI91-948)

Fournisseur: ProSci Inc.

Description: Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyses the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI92-058)

Fournisseur: ProSci Inc.

Description: Carbonic Anhydrase-Related Protein 10 (CA10) belongs to the Carbonic Anhydrase family of Zinc Metalloenzymes. It is an acatalytic member of the alpha-carbonic anhydrase subgroup. CA10 expression is detected in the adult total brain and almost all parts of the central nervous system, but not in the fetal brain. CA10 catalyse the reversible hydration of carbon dioxide in various biological processes, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. It is thought to play a role in the central nervous system, especially in brain development.

UOM: 1 * 50 µG

*Promo

Référence Produit: (PRSI91-650)

Fournisseur: ProSci Inc.

Description: Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the alpha-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyse the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA11 is expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid. CA11 may play a general role in the central nervous system.

UOM: 1 * 50 µG

*Promo

Référence Produit: (70856-3)

Fournisseur: Merck Millipore (Novagen)

Description: Convenient solution for selective degradation of RNA.

UOM: 1 * 1 mL

*Promo

Référence Produit: (325896-10)

Fournisseur: Merck Millipore (Calbiochem‎)

Description: Recombinant, human Wee1 fused at the N-terminus to a GST-His6-thrombin cleavage site sequence and expressed in <i>S. frugiperda</i> insect cells using a baculovirus expression system.

UOM: 1 * 10 µG

*Promo

Fournisseur: Merck Millipore (Calbiochem‎)

Description: Bovine thrombin (from plasma)

Référence Produit: (605157-1)

Fournisseur: Merck Millipore (Calbiochem‎)

Description: Bovine thrombin (from plasma)

UOM: 1 * 1 KU

*Promo