Votre recherche pour: D-Glucono-1,5-lactone

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Anti-IL-15 Rabbit Monoclonal Antibody [clone: EPR1542Y]

Fournisseur: Abcam

Description: Rabbit monoclonal [EPR1542Y] to IL-15.

Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI3G8]

Référence Produit: (ABCAAB119774-100)

Fournisseur: Abcam

Description: Mouse monoclonal [OTI3G8] to 15 Lipoxygenase 1.

UOM: 1 * 100 µl

*Promo

N/A Pièce

Anti-GAL4 Mouse Monoclonal Antibody [clone: 15-6E10A7]

Référence Produit: (ABCAAB135397-100)

Fournisseur: Abcam

Description: Mouse monoclonal [15-6E10A7] to GAL4.

UOM: 1 * 100 µG

*Promo

N/A Pièce

15-HETE ELISA Kit

Référence Produit: (ANTIA74043-96)

Fournisseur: ANTIBODIES.COM

Description: 15-HETE ELISA kit is a competitive Enzyme-Linked Immunosorbent Assay (cELISA) designed for the in vitro quantitative determination of 15-HETE in serum, plasma, tissue homogenates, and other biological fluids.

UOM: 1 * 96 Tests

New Product *Promo

N/A Pièce

Human IL-15 peptide

Référence Produit: (PRSI7231P)

Fournisseur: ProSci Inc.

Description: 13 amino acid peptide near the center of human IL-15.

UOM: 1 * 50 µG

*Promo

N/A Pièce

Human Recombinant IL-15

Fournisseur: STEMCELL Technologies

Description: Interleukin 15 (IL-15) is a four-alpha helix bundle cytokine with many similar properties to IL-2, with which it shares components of its receptor. The IL-15 receptor is a heterotrimeric receptor composed of IL-15Ra, the high-affinity receptor for IL-15, as well as IL-2/15Rb (CD122) and common gamma chain (CD132). IL-15 binds to IL-15Rα receptor and can then be presented in trans to IL-2/15Rb and common gamma chain on other cells. Trans-presentation is thought to be the major mechanism by which IL-15-mediated responses occur in mice, although may not be necessary in humans (Castillo et al.). The cytoplasmic domains of IL-2/15Rb and common gamma chain mediate signaling to activate JAK/STAT and PI3K pathways. IL-15 supports the survival and proliferation of naive CD4+ and CD8+ T cells, and promotes homeostasis of memory T cells. IL-15 also promotes the survival and differentiation of NK cells and regulates their cytolytic activity (Ma et al.).

VWR® VisiScope®, Oculaires pour stéréomicroscopes à zoom

Référence Produit: (630-1780)

Fournisseur: VWR Collection

Description: Oculaires, VWR® VisiScope®, 15× (15 mm)

UOM: 1 * 2 Pce

*Promo

N/A Pièce

Human recombinant IL-15 R alpha & IL-15 fusion (from Cells)

Référence Produit: (PRSI92-588)

Fournisseur: ProSci Inc.

Description: Interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs.

UOM: 1 * 50 µG

*Promo