Votre recherche pour: C6+NBD-Ceramide

Fournisseur: ENZO LIFE SCIENCES

Description: Purified from bovine brain. Contains primarily stearic and nervoic acids. Precursor to ceramide second messengers via the action of sphingomyelinase.

New Product

Référence Produit: (BOSSBS-4216R-CY5)

Fournisseur: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-4216R-CY7)

Fournisseur: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

*Promo

Référence Produit: (USBIC7850-35G-APC)

Fournisseur: US Biological

Description: Anti-C6 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

UOM: 1 * 200 µl

*Promo

Référence Produit: (USBIC7850-35G-FITC)

Fournisseur: US Biological

Description: Anti-C6 Rabbit Polyclonal Antibody (FITC (Fluorescein))

UOM: 1 * 200 µl

*Promo

Référence Produit: (BOSSBS-4216R-HRP)

Fournisseur: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-4216R-A680)

Fournisseur: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically Recognises the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-4277R)

Fournisseur: Bioss

Description: Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.

UOM: 1 * 100 µl

*Promo

Fournisseur: Apollo Scientific

Description: GW4869 2HCl is a cell permeable, selective and non-competitve inhibitor of N-SMase (neutral sphingomyelinase), which is important in the metabolism of sphingomyelin producing ceramide and phosphocholine and in cell signaling and regulation.

Référence Produit: (BOSSBS-6873R)

Fournisseur: Bioss

Description: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].

UOM: 1 * 100 µl

*Promo

Fournisseur: ENZO LIFE SCIENCES

Description: Ceramide synthase inhibitor

New Product

Référence Produit: (BOSSBS-4127R-A350)

Fournisseur: Bioss

Description: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA = PA >C-1-P >S-1-P. May be involved in cell adhesion and in cell-cell interactions.

UOM: 1 * 100 µl

*Promo

Référence Produit: (USBI137889)

Fournisseur: US Biological

Description: Anti-C6 Goat Polyclonal Antibody

UOM: 1 * 1 mL

*Promo

Fournisseur: Cayman Chemical

Description: Fumonisin B₁ is a mycotoxin produced from <i>F. moniliforme</i>, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase)

FDS (Fiche de données de sécurité)

Référence Produit: (USBIC7850-35G-BIOT)

Fournisseur: US Biological

Description: Anti-C6 Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

*Promo

Référence Produit: (BOSSBS-4127R-CY7)

Fournisseur: Bioss

Description: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA = PA >C-1-P >S-1-P. May be involved in cell adhesion and in cell-cell interactions.

UOM: 1 * 100 µl

*Promo