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Product Image-186961000.

Sulfure de dimethyle-borane 2 M dans le toluène, AcroSeal®

Fournisseur: Thermo Fisher Scientific
Description: Sulfure de dimethyle-borane 2 M dans le toluène, AcroSeal®

FDS (Fiche de données de sécurité)

Product Image-86180.260

Ferroïne (Phénanthroline-1,10-fer(II) sulfate) 1/40 mol/l, AVS TITRINORM indicateur redox

Fournisseur: VWR Chemicals
Description: Ferroïne (Phénanthroline-1,10-fer(II) sulfate) 1/40 mol/l, AVS TITRINORM indicateur redox

FDS (Fiche de données de sécurité) Certificats.

Image Unavailable-BOSSBS-0742R-CY5

Anti-CDKN1B Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-0742R-CY5)
Fournisseur: Bioss
Description: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
UOM: 1 * 100 µl
Product Image-445278000.

Trifluoro(méthanol)bore 12% 1.5 M dans le methanol, AcroSeal®

Fournisseur: Thermo Fisher Scientific
Description: Trifluoro(méthanol)bore 12% 1.5 M dans le methanol, AcroSeal™

FDS (Fiche de données de sécurité)

Image Unavailable-BOSSBS-8116R-CY3

Anti-COA3 Rabbit Polyclonal Antibody (Cy3®)

Référence Produit: (BOSSBS-8116R-CY3)
Fournisseur: Bioss
Description: Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9766R-A680

Anti-INTS3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-9766R-A680)
Fournisseur: Bioss
Description: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent Signalling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilisation of the complex at DNA damage sites.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7848R

Anti-SKA3 Rabbit Polyclonal Antibody

Référence Produit: (BOSSBS-7848R)
Fournisseur: Bioss
Description: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.
UOM: 1 * 100 µl
Product Image-ABCAAB249620-100

Anti-AP-2 complex subunit alpha-1 Rabbit Monoclonal Antibody [clone: EPR7573(2)(B)]

Fournisseur: Abcam
Description: Rabbit monoclonal [EPR7573(2)(B)] to AP-2 complex subunit alpha-1 - BSA and Azide free.

Image Unavailable-BOSSBS-4139R-CY7

Anti-NFKBIE Rabbit Polyclonal Antibody (Cy7®)

Référence Produit: (BOSSBS-4139R-CY7)
Fournisseur: Bioss
Description: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12520R-CY3

Anti-ARID1B Rabbit Polyclonal Antibody (Cy3®)

Référence Produit: (BOSSBS-12520R-CY3)
Fournisseur: Bioss
Description: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
UOM: 1 * 100 µl
Image Unavailable-42967.AP

Sulfure de dimethyle-borane

Fournisseur: Thermo Fisher Scientific
Description: Packaged under Argon in resealable ChemSeal® bottles

FDS (Fiche de données de sécurité) Certificats.

Image Unavailable-BOSSBS-0024M-A680

Anti-PSEN1 Mouse Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-0024M-A680)
Fournisseur: Bioss
Description: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyses the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0024M-A750

Anti-PSEN1 Mouse Polyclonal Antibody (Alexa Fluor® 750)

Référence Produit: (BOSSBS-0024M-A750)
Fournisseur: Bioss
Description: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyses the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0730R-CY5

Anti-HSPB1 Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-0730R-CY5)
Fournisseur: Bioss
Description: Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as chaperones that bind to and stabilize the active conformation of other proteins. HSP27, along with other members of the small HSP group, possesses a C-terminal Alpha-crystalline homology domain. HSP27 is localized to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, where it may function to stabilize DNA and/or the nuclear membrane. Cytoplasmic HSP27 exists in multiple complexes. One complex consists of HSP27, Akt (PKB), MAPKAP-kinase 2, and p38 MAPK. The presence of HSP27 in this complex is required for Akt activation by stress stimuli. Another complex consists of HSP27 and the IKK complex. HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, thereby inhibiting filament extension. Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, and stimulates HSP27 binding to the IKK complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0730R-A680

Anti-HSP27 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Référence Produit: (BOSSBS-0730R-A680)
Fournisseur: Bioss
Description: Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as chaperones that bind to and stabilise the active conformation of other proteins. HSP27, along with other members of the small HSP group, possesses a C-terminal Alpha-crystalline homology domain. HSP27 is localised to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, where it may function to stabilise DNA and/or the nuclear membrane. Cytoplasmic HSP27 exists in multiple complexes. One complex consists of HSP27, Akt (PKB), MAPKAP-kinase 2, and p38 MAPK. The presence of HSP27 in this complex is required for Akt activation by stress stimuli. Another complex consists of HSP27 and the IKK complex. HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, thereby inhibiting filament extension. Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, and stimulates HSP27 binding to the IKK complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0660R-CY5

Anti-CCND3 Rabbit Polyclonal Antibody (Cy5®)

Référence Produit: (BOSSBS-0660R-CY5)
Fournisseur: Bioss
Description: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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