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Référence Produit: (BOSSBS-2358R-A350)
Fournisseur: Bioss
Description: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-2358R-CY3)
Fournisseur: Bioss
Description: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-2358R-A555)
Fournisseur: Bioss
Description: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Fournisseur: ENZO LIFE SCIENCES
Description: The Screen-Well™ Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, gamma-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.

Référence Produit: (BOSSBS-2358R-A750)
Fournisseur: Bioss
Description: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Référence Produit: (BOSSBS-8634R-HRP)
Fournisseur: Bioss
Description: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate; FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription; required for ESR1 binding to the NKX2-1 promoter in breast cancer cells; binds to the RPRM promter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.
UOM: 1 * 100 µl


Référence Produit: (MDT100-1KT)
Fournisseur: SIGMA ALDRICH MICROSCOPY
Description: Designed for orientation of excised surgical specimens. This method of permanently marking the margins of tissue specimens is very beneficial to surgeon and pathologists testing for skin cancer.
UOM: 1 * 1 KIT


Référence Produit: (A-127-6X1.2ML)
Fournisseur: Merck
Description: A multicomponent calibration kit containing acetone, ethanol, isopropanol, and methanol at concentrations of 100, 250, 500, 1000, 2000, and 4000 μg/mL. This kit is suitable for calibration of blood alcohol testing methods using GC Headspace.
UOM: 1 * 6 Pce


Référence Produit: (PROONIST-610)
Fournisseur: LGC Standards PROMOCHEM
Description: This standard reference material is intended to facilitate the development of chemical methods of analysis for trace elements.
UOM: 1 * 1 Pce


Référence Produit: (ENZOENZ450140100)
Fournisseur: ENZO LIFE SCIENCES
Description: Rapid, reliable method to isolate histone proteins in mammalian cells and tissues for histone modification applications.
UOM: 1 * 1 KIT


Fournisseur: COLLECTION PREFIX HPLC
Description: ChromSwordAuto® 5: Communicates directly with the HPLC instrument in order to create a fully automated HPLC or UHPLC method development station. The unique ChromSwordAuto® software is capable of developing and optimising HPLC methods fully automatically within just a few hours. Methods already in use can also be optimised, thus reducing analysis time considerably. All you have to do is place the sample in the autosampler, set a few parameters and start the optimisation process. ChromSwordAuto® then predicts the method conditions and controls the HPLC system connected in recording the chromatograms. These are analysed by the software and the optimal conditions determined. The rapid optimisation mode can be used to provide an overview of the performance of the column/solvent system selected or to rapidly screen columns and eluents considered for use. The fine optimisation mode additionally collects and evaluates further ancillary data and produces up to 10 sets of alternative optimal HPLC conditions. Both of these operating modes can be applied in combination with column and solving switching procedures in order to try a variety of column/solvent combinations or to establish optimal pH conditions – fully automatically.
Main features include:

Fournisseur: Merck
Description: Multi-component calibration kits containing acetone, ethanol, isopropanol, and methanol varying concentrations. These kits ares suitable for calibration of blood alcohol testing methods using GC Headspace.
Référence Produit: (PROOLGC7162)
Fournisseur: LGC Standards PROMOCHEM
Description: Cette norme est destinée à être utilisée pour le développement, la validation et le contrôle de qualité des méthodes analytiques pour la détermination des éléments dans la végétation.
UOM: 1 * 20 g


Référence Produit: (TDF100A-1KT)
Fournisseur: Merck
Description: This assay determines the total dietary fiber content of food using a combination of enzymatic and gravimetric methods. Samples of dried, fat-free foods are gelatinised with heat stable α-amylase and then enzymatically digested with protease and amyloglucosidase to remove the protein and starch present in the sample.
UOM: 1 * 1 KIT


Référence Produit: (1.04140.0001)
Fournisseur: Merck
Description: La plupart des individus infectés par Salmonella développent de la diarrhée, de la fièvre et des crampes abdominales 12 à 72 h après l'infection. La maladie dure généralement de 4 à 7 jours et la majorité des patients guérissent sans traitement. Cependant, dans certains cas, la diarrhée peut être si grave qu'une hospitalisation est nécessaire. Salmonella est un genre de bactéries en forme de bâtonnet, à Gram négatif, non sporulées, à prédominance mobile, appartenant à la famille des entérobactéries. Salmonella spp. sont l'une des causes les plus courantes d'intoxication alimentaire dans le monde et ont été isolées de la plupart des types d'aliments crus (par exemple, les viandes, les œufs et les produits végétaux). Leur haute résistance au séchage combinée à une très haute résistance à la chaleur une fois séchée fait de Salmonella un problème potentiel dans la plupart des aliments, en particulier dans les produits secs et semi-secs. La législation alimentaire dans de nombreux pays inclut des limites pour Salmonella - généralement l'absence dans 25 g de nourriture. Les méthodes microbiologiques traditionnelles de détection de Salmonella dans l'alimentation humaine et animale nécessitent jusqu'à cinq jours au total pour obtenir un simple résultat oui/non. Des tests innovants et rapides facilitent le dépistage des organismes pathogènes. Le format en une étape réduit la possibilité d'erreurs lors de la manipulation.
UOM: 1 * 25 Tests

Référence Produit: (CAYM700420-96)
Fournisseur: Cayman Chemical
Description: A kit for measuring ascorbate.
UOM: 1 * 1 Pce


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