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Image Unavailable-BOSSBS-3967R-A647

Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-3967R-A647)
Fournisseur: Bioss
Description: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3967R-A350

Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Référence Produit: (BOSSBS-3967R-A350)
Fournisseur: Bioss
Description: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6163R-A555

Anti-DIRAS1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-6163R-A555)
Fournisseur: Bioss
Description: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis.DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6163R-HRP

Anti-DIRAS1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-6163R-HRP)
Fournisseur: Bioss
Description: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis.DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
UOM: 1 * 100 µl
Image Unavailable-CORN6859

Accessories for bottle top dispensers

Fournisseur: Corning
Description: BTD volume rocker switch, 100 ml , Corning®

Image Unavailable-BOSSBS-1442R-A555

Anti-Arfaptin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-1442R-A555)
Fournisseur: Bioss
Description: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1442R-A647

Anti-Arfaptin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Référence Produit: (BOSSBS-1442R-A647)
Fournisseur: Bioss
Description: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.
UOM: 1 * 100 µl
Image Unavailable-SHBT200-70AF-100UG

Mouse Recombinant IL-21 (Animal free) (from E. coli)

Fournisseur: Shenandoah Biotechnology
Description: Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with interleukin 4 (IL-4) for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.

New Product

Image Unavailable-BOSSBS-1442R-A350

Anti-Arfaptin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Référence Produit: (BOSSBS-1442R-A350)
Fournisseur: Bioss
Description: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5330R-HRP

Anti-RHOA Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Référence Produit: (BOSSBS-5330R-HRP)
Fournisseur: Bioss
Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5330R-CY5.5

Anti-RHOA Rabbit Polyclonal Antibody (Cy5.5®)

Référence Produit: (BOSSBS-5330R-CY5.5)
Fournisseur: Bioss
Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UOM: 1 * 100 µl
Product Image-BOSSBS-4002R-CY7

Anti-PRKAA1 Rabbit Polyclonal Antibody (Cy7®)

Référence Produit: (BOSSBS-4002R-CY7)
Fournisseur: Bioss
Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2583R-A750

Anti-ICOS/CD278 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Référence Produit: (BOSSBS-2583R-A750)
Fournisseur: Bioss
Description: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5330R-FITC

Anti-RHOA Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-5330R-FITC)
Fournisseur: Bioss
Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5330R-A555

Anti-RHOA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Référence Produit: (BOSSBS-5330R-A555)
Fournisseur: Bioss
Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4002R-FITC

Anti-PRKAA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Référence Produit: (BOSSBS-4002R-FITC)
Fournisseur: Bioss
Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
UOM: 1 * 100 µl
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 01 45 14 89 12.
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