Votre recherche pour: Milieux pour microbiologie

Référence Produit: (BOSSBS-4736R-A488)

Fournisseur: Bioss

Description: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-4736R-A350)

Fournisseur: Bioss

Description: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-6818R-CY7)

Fournisseur: Bioss

Description: Not known, though may play a role in tumor transformation or aspects of tumor progression.Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-3738R-CY3)

Fournisseur: Bioss

Description: Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-2969R-A350)

Fournisseur: Bioss

Description: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-2969R-A488)

Fournisseur: Bioss

Description: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-0480R-CY5)

Fournisseur: Bioss

Description: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-0481R-CY3)

Fournisseur: Bioss

Description: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-0481R-CY5)

Fournisseur: Bioss

Description: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-6165R-CY5.5)

Fournisseur: Bioss

Description: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-0817R-A680)

Fournisseur: Bioss

Description: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognised on a melanoma by autologous cytolytic T-lymphocytes.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-5957R-FITC)

Fournisseur: Bioss

Description: Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).

UOM: 1 * 100 µl

*Promo

Fournisseur: ENZO LIFE SCIENCES

Description: Potent antitumor antibiotic. Inhibitor of pp60^src tyrosine kinase and of c-myc gene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src, and yes.

Fournisseur: VWR Collection

Description: Ce portoir de stockage PCR de conception élégante et moderne inclut un couvercle unique d’où le portoir sort et pivote de 180° pour se transformer en un support pratique sur lequel le portoir va reposer. Des poignées texturées et ergonomiques procure un maintien sûr, réduisent les risques de faire tomber le portoir PCR, facilitant ainsi la manipulation et le transport, en particulier lors du port de gants.

Référence Produit: (USBIT8250-10C)

Fournisseur: US Biological

Description: Anti-TGFA Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 50 µG

*Promo

Référence Produit: (USBIT0300-01)

Fournisseur: US Biological

Description: Anti-TACC3 Goat Polyclonal Antibody

UOM: 1 * 100 µG

*Promo