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Image Unavailable-BOSSBS-12397R-A647

Anti-MAML2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Notch receptors are involved in cell-fate determination in organisms as diverse as flies, frogs, and humans (1). The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2). In Drosophila, loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2). The human homolog, mastermind-like 1 (Mam1), localizes to nuclear bodies (2-4). Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, forms a DNA-binding complex with ICN and RBP-Jk, and amplifies Notch-induced transcription of Hes1 (2). Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5). The gene which encodes Mam1 maps to human chromosome 5 (4).
Référence Produit: BOSSBS-12397R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4002R-A680

Anti-AMPK alpha-1/2 Thr183/Thr172 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Référence Produit: BOSSBS-4002R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4002R-A350

Anti-PRKAA1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].
Référence Produit: BOSSBS-4002R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-10466R-A555

Anti-RHOG Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011].
Référence Produit: BOSSBS-10466R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6163R-CY3

Anti-DIRAS1 Rabbit Polyclonal Antibody (Cy3®)

Description: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis.DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
Référence Produit: BOSSBS-6163R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-3967R-CY7

Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Cy7®)

Description: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
Référence Produit: BOSSBS-3967R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-3967R-A680

Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
Référence Produit: BOSSBS-3967R-A680
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-12880R-CY3

Anti-BOLL Rabbit Polyclonal Antibody (Cy3®)

Description: Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency.
Référence Produit: BOSSBS-12880R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-612-0776

Accessoires pour bec Bunsen, Fireboy plus

Description: Foot switch with connecting cable for fireboy/Dose It (not suitable for VacuSafe)
Référence Produit: 612-0776
UOM: 1 * 1 Pce
Fournisseur: Integra
Product Image-WHEAI050694

'Accessories for peristaltic pumps, Omnispense® Plus, Wheat

Description: Foot switch, Pour: Peristaltic pumps Omnispense® Plus and Unispense® µP
Référence Produit: WHEAI050694
UOM: 1 * 1 Pce
Fournisseur: DWK Life Sciences
Image Unavailable-BOSSBS-10466R-CY7

Anti-RHOG Rabbit Polyclonal Antibody (Cy7®)

Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011].
Référence Produit: BOSSBS-10466R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-3967R-A488

Anti-AMPK beta 1 + 2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
Référence Produit: BOSSBS-3967R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6163R-A488

Anti-DIRAS1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis.DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
Référence Produit: BOSSBS-6163R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-12880R

Anti-BOLL Rabbit Polyclonal Antibody

Description: Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency.
Référence Produit: BOSSBS-12880R
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-HUBE6152

Accessories for Huber thermostats and baths

Description: Float switch, Pour: Leak monitoring
Référence Produit: HUBE6152
UOM: 1 * 1 Pce
Fournisseur: HUBER
Product Image-554-2669

Vannes haute pression MXP, Rheodyne®, MX Series II™

Description: Ces vannes actionnées à haute pression sont conçues pour être ajoutées à un instrument existant ou pour fonctionner de manière optimale avec des configurations de laboratoire autonomes.
Référence Produit: 554-2669
UOM: 1 * 1 Pce
Fournisseur: IDEX RHEODYNE
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