Imprimer

Rhodamine 123 fluorescent dye, dye_mitochondria

Marques : SIGMA ALDRICH MICROSCOPY
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

Synonyme(s): 3,6-Diamino-9-(2-(methoxycarbonyl)phenyl xanthylium chloride, 3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride, 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester

MQ100

R8004-100MG R8004-25MG R8004-5MG
R8004-100MGEA 641 EUR
R8004-100MG R8004-25MG R8004-5MG
Rhodamine 123 fluorescent dye, dye_mitochondria
Rhodamine 123

Rhodamine 123 is useful as a laser dye and to have selective cell growth effects. It has also been used to measure mitochondrial membrane potential.


Rhodamine 123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for P-glycoprotein (Pgp). It is part of the rhodamine family of flurone dyes. The dye is mostly used to assess mitochondrial bioenergetics in living cells. Functional assays for multi-drug resistance (MDR) proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of multi-drug resistance protein-1 (MRP1).


Fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of MRP1.

Formule: C₂₁H₁₇ClN₂O₃
Poids moléculaire: 380.82 g/mol
Température de stockage: Room Temperature
Numéro MDL: MFCD00012664
Numéro CAS: 62669-70-9
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=8715b9096798f275fea230ef7ef997c48f67619c&vid=8715b9096798f275fea230ef7ef997c48f67619c&prid=web&clid=SAPDAM

Commander maintenant

Résultats des tests de spécification

Appearance (Form) Powder
Infrared spectrum Conforms to Structure
Carbon (dry basis) 62.2 - 70.2 %
Nitrogen (dry basis) 6.9 - 7.8 %
Water (by Karl Fischer) ≤10.0 %
Solubility (Turbidity)
1mg/ml in Ethanol
Clear to Slightly Hazy
Solubility (Colour) Conforms to Requirements
Yellow-Orange
Recommended Retest Period 4 Years


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Plus About VWR