IM-54 ≥98% (par HPLC)
Marques : ENZO LIFE SCIENCESTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Synonyme(s):
1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione
Cell permeable inhibitor of necrosis. Selectively blocks oxidative stress-induced necrotic cell death (~3 µm IM-54 prevented ~50% cell death in HL60 cells exposed to 100 µm H2O2). Does not protect against etoposide-induced apoptosis or display antioxidant properties. Does not affect S6K1 and PKC kinase activities at concentrations of 50 µm.
Formule:
C₁₉H₂₃N₃O₂ |
Numéro MDL:
MFCD18382109 Numéro CAS: 861891-50-1 |
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