KN-93 (water soluble) ≥98% (par 1H-RMN)
Marques : ENZO LIFE SCIENCESTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Synonyme(s):
(E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate, (E)-KN-93 phosphate
CaM kinase II inhibitor
Selective inhibitor of rat brain Ca²⁺/calmodulin-dependent protein kinase II. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets of Langerhans. Has no significant effect on protein kinase A (PKA) activity. Induces G1 cell cycle arrest and apoptosis in NIH 3T3 cells.
Formule:
C₂₆H₂₉ClN₂O₄S·H₃PO₄ Poids moléculaire: 501.0·98.0 g/mol |
Numéro MDL:
MFCD03788201 Numéro CAS: 1188890-41-6 | 139298-40-1 (free base) |
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