A77 1726 ≥98% (par HPLC)
Marques : Enzo Life SciencesTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Dihydrorotate dehydrogenase inhibitor
Physiologically active metabolite of the immunosuppressive drug leflunomide (Prod. No. ALX-430-095). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also inhibits the activity of cyclooxygenase-2 (COX-2) in vitro and in vivo.
Formule:
C₁₂H₉F₃N₂O₂ |
Numéro MDL:
MFCD00910058 Numéro CAS: 108605-62-5 |
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