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A77 1726 ≥98% (par HPLC)

Marques : Enzo Life Sciences
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Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

ALX430096M005 ALX430096M025
ENZOALX430096M005EA 94.6 EUR
ENZOALX430096M005 ENZOALX430096M025
A77 1726 ≥98% (par HPLC)
A77 1726

Dihydrorotate dehydrogenase inhibitor


Physiologically active metabolite of the immunosuppressive drug leflunomide (Prod. No. ALX-430-095). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also inhibits the activity of cyclooxygenase-2 (COX-2) in vitro and in vivo.

Formule: C₁₂H₉F₃N₂O₂
Numéro MDL: MFCD00910058
Numéro CAS: 108605-62-5

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