[-]-Deguelin ≥95% (par HPLC)
Marques : ENZO LIFE SCIENCESTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Synonyme(s):
Deguelin, (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one, (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one
COX-2 inhibitor
Inhibitor of Akt (protein kinase B; PKB) in an in vitro lung carcinogenesis progression model. Inhibits cell proliferation - cells accumulate in the G2-M phase of the cell cycle. Premalignant and malignant human brochial epithelial cells are highly sensitive to deguelin compared to normal cells. Induces apoptosis. Exhibits a marked inhibitory effect on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test. Inhibits cyclooxygenase-2 (COX-2) expression.
Formule:
C₂₃H₂₂O₆ Température de stockage: Réfrigérateur |
Numéro MDL:
MFCD01740600 Numéro CAS: 522-17-8 |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...