trans-Ned-19
Marques : ENZO LIFE SCIENCESTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Cell permeable, selective and potent inhibitor of nicotinic acid adenine dinucleotide phosphate (NAADP) receptor in mammalian cells and sea urchin eggs. Blocks NAADP signaling. Inhibits Ca2+ release: trans-Ned-19 (IC50 = 6nM); cis-Ned-19 (IC50 = 800nM). [32P] NAADP binding: trans-Ned-19 (IC50 = 0.4nM); cis-Ned-19 (IC50 = 15µM).
Inhibits Ca2+ release from lysosomes. Noncompetitive antagonist. Fluorescent.
Synthetic
Formule:
C₃₀H₃₁FN₄O₃ Poids moléculaire: 514.601 g/mol |
Numéro MDL:
MFCD02057367 Numéro CAS: 1354235-96-3 |
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