Indirubin ≥98% (par 1H-RMN, HPLC)
Marques : ENZO LIFE SCIENCESTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Synonyme(s):
Indigo Red, [2,3'-Biindolinylidene]-2',3-dione
Inhibitor of CDK and GSK
Inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) and of GSK-3beta (IC50=600nM). Inhibits inflammatory reaction in delayed-type hypersensitivity in mice. Ligand of human aryl hydrocarbon receptor. Exhibits anti-cancer activity.
Synthetic.
Formule:
C₁₆H₁₀N₂O₂ Poids moléculaire: 262.27 g/mol |
Numéro MDL:
MFCD00221745 Numéro CAS: 479-41-4 |
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