Imprimer

Indirubin ≥98% (par 1H-RMN, HPLC)

Marques : ENZO LIFE SCIENCES
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

Synonyme(s): Indigo Red, [2,3'-Biindolinylidene]-2',3-dione

ALX270361M001 ALX270361M005
ENZOALX270361M001EA 84.7 EUR
ENZOALX270361M001 ENZOALX270361M005
Indirubin ≥98% (par 1H-RMN, HPLC)
Indirubin

Inhibitor of CDK and GSK


Inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) and of GSK-3beta (IC50=600nM). Inhibits inflammatory reaction in delayed-type hypersensitivity in mice. Ligand of human aryl hydrocarbon receptor. Exhibits anti-cancer activity.


Synthetic.

Formule: C₁₆H₁₀N₂O₂
Poids moléculaire: 262.27 g/mol
Numéro MDL: MFCD00221745
Numéro CAS: 479-41-4

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