Bisindolylmaleimide I ≥98% (par CCM)
Marques : ENZO LIFE SCIENCESTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
Synonyme(s):
GF 109203X
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
- PKC inhibitor
Red solid.
Soluble in dimethyl formamide or DMSO (10mg/ml, warm to 40°C and vortex well).
Formule:
C₂₅H₂₄N₄O₂ Température de stockage: Congélateur |
Numéro MDL:
MFCD00236428 Numéro CAS: 133052-90-1 |
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