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Cerulenin ≥98% (par CCM)

Marques : ENZO LIFE SCIENCES
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BMLG2370005 BMLG2370025
ENZOBMLG2370005EA 165 EUR
ENZOBMLG2370005 ENZOBMLG2370025
Cerulenin ≥98% (par CCM)
Cerulenin

Fatty acid synthase inhibitor


Antibiotic. Fatty acid synthase (FAS) inhibitor reported to bind in equimolar ratio to β-keto-acyl-ACP synthase (KAS; IC50=1.5µM), thus inhibiting protein acylation at concentrations of 45-134 µM. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).

Formule: C₁₂H₁₇NO₃
Numéro MDL: MFCD00077686
Numéro CAS: 17397-89-6
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