Imprimer

Propyle hydroxy-4 benzoate 99.0-100.5% (par HPLC), EMPROVE® ESSENTIAL FCC, BP, Ph. Eur., JP, NF suitable for use as excipient E216, SAFC®

Marques : MERCK PRODUCTION CHEMICALS
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

Attention

Synonyme(s): Propylparabene, 4-Hydroxybenzoate de propyle

1.07427.5000 1.07427.9029
1.07427.5000EA 1100 EUR
1.07427.5000 1.07427.9029
Propyle hydroxy-4 benzoate 99.0-100.5% (par HPLC), EMPROVE® ESSENTIAL FCC, BP, Ph. Eur., JP, NF suitable for use as excipient E216, SAFC®
Propyle hydroxy-4 benzoate
Formule: C₁₀H₁₂O₃
Poids moléculaire: 180.2 g/mol
Point d'ébullition: 292
Point de fusion: 95
Densité: 1.28 g/cm³ (20 °C)
Température de stockage: Température ambiante
Numéro MDL: MFCD00002354
Numéro CAS: 94-13-3
EINECS: 202-307-7
Indice Merck: 13,07958

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Résultats des tests de spécification

Assay (by Acidimetry following Saponification) 98.0 - 102.0%
Assay (HPLC) 99.0 - 100.5%
Identity Passes Test
Appearance of Solution Passes Test
Acidic Substances Passes Test
Melting range (Lower Value) ≥96 °C
Melting range (Upper Value) ≤98 °C
Heavy metals (as Pb) ≤10 ppm
As (Arsenic) ≤3 ppm
Cd (Cadmium) ≤10 ppm
Cu (Copper) ≤10 ppm
Hg (Mercury) ≤1 ppm
Pb (Lead) ≤2 ppm
Zn (Zinc) ≤10 ppm
Related Substances (HPLC) Passes Test
p-Hydroxy Benzoic Acid ≤0.5%
Sum of all Impurities ≤1.0%
Largest Unspecified Impurity ≤0.5%
1-Propylalcohol (HS-GC) ≤5000 ppm
Other Residual Solvents (ICH Q3C) Excluded by Manufactoring Process
Sulfated Ash ≤0.05%
Loss on Drying (80 °C) ≤0.5%
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP ,JP, NF, FCC.


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