IL-17A exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.
Flow Cytometry: (1:20-1:500). Optimal conditions must be determined individually for each application.
Type: Primary
Antigen: IL17A
Clonality: Monoclonal
Clone: 17-142F
Conjugation: FITC
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human