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Anti-MYOG Mouse Monoclonal Antibody [clone: MGN185 F5D]

Fournisseur: Biotium
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

BNUB1233-500 BNUB1233-100
BNUB1233-500EA 511 EUR
BNUB1233-500 BNUB1233-100
Anti-MYOG Mouse Monoclonal Antibody [clone: MGN185 F5D]
Anticorps
Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.

  • Purified

Type: Primary
Antigen: MYOG
Clonality: Monoclonal
Clone: MGN185 F5D
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cat, Human, Mouse, Pig, Rat
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