Recognizes a 34 kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Type: Primary
Antigen: CDC2
Clonality: Monoclonal
Clone: CDK1/873
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Cow, Human, Mink, Monkey