This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
Type: Primary
Antigen: AFP
Clonality: Monoclonal
Clone: C2 C3 MBS-12
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human