Imprimer

Anti-CGB Mouse Monoclonal Antibody (CF405S) [clone: HCGb/211]

Fournisseur: Biotium
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

BNC040459-500 BNC040459-100
BNC040459-500EA 560 EUR
BNC040459-500 BNC040459-100
Anti-CGB Mouse Monoclonal Antibody (CF405S) [clone: HCGb/211]
Anticorps
This MAb reacts with a protein of 22 kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Type: Primary
Antigen: CGB
Clonality: Monoclonal
Clone: HCGb/211
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
Commander maintenant

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