Imprimer

Anti-MS4A1 Mouse Monoclonal Antibody (Biotin) [clone: 109-3C2]

Fournisseur: Biotium
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

BNCB0355-500 BNCB0355-100
BNCB0355-500EA 560 EUR
BNCB0355-500 BNCB0355-100
Anti-MS4A1 Mouse Monoclonal Antibody (Biotin) [clone: 109-3C2]
Anticorps
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.

Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: 109-3C2
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG3 kappa
Reactivity: Human
Commander maintenant

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