Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
Type: Primary
Antigen: CD48
Clonality: Monoclonal
Clone: 156-4H9
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human