Imprimer

Anti-MAGEA1 Mouse Monoclonal Antibody (CF488A) [clone: MA454]

Fournisseur: Biotium
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

BNC880008-500 BNC880008-100
BNC880008-500EA 560 EUR
BNC880008-500 BNC880008-100
Anti-MAGEA1 Mouse Monoclonal Antibody (CF488A) [clone: MA454]
Anticorps
Recognizes a protein of 42-46 kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8 T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Type: Primary
Antigen: MAGEA1
Clonality: Monoclonal
Clone: MA454
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Dog, Human, Rat
Commander maintenant

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Plus About VWR