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Butyrolactone 3 ≥95%, solide cristallin

Marques : Cayman Chemical
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : 0.0 sur 5

12095-1 12095-5
CAYM12095-1EA 85.7 EUR
CAYM12095-1 CAYM12095-5
Butyrolactone 3 ≥95%, solide cristallin
Butyrolactone 3

Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 μM and has an affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 can inhibit pre-RNA splicing with an IC50 value of 0,5 mM and as such has been used to investigate Gcn5/PCAF-like HAT functions during assembly of spliceosome before pre-mRNA translation.


Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes.

Formule: C₉H₁₂O₄
Température de stockage: Congélateur
Numéro MDL: MFCD08702690
Numéro CAS: 778649-18-6

Commander maintenant

Résultats des tests de spécification

Purity ≥95%
Formal Name rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid
Formulation A Crystalline Solid
SMILES O=C1C([C@@H](C(O)=O)[C@H](CCC)O1)=C
InChI Code 1S/C9H12O4/c1-3-4-6-7(8(10)11)5(2)9(12)13-6/h6-7H,2-4H2,1H3,(H,10,11)/t6-,7+/m0/s1
InChI Key SRQUTZJZABSZRQ-NKWVEPMBSA-N
Storage −20 °C
Shipping Room temperature in continental US; may vary elsewhere
Stability 2 years from the QC date provided on the Certificate of Analysis, when stored properly


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