The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7.
The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.
Type: Primary
Antigen: MHC II (I-A/I-E) (MHC II (I-A/I-E))
Clonality: monoclonal
Clone: M5/115.15.2
Conjugation: FITC (Fluorescein)
Epitope:
Host: Rat
Isotype: IgG2b Kappa
Reactivity: Mouse