The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells.
Type: Primary
Antigen: IL2RA (interleukin 2 receptor, alpha)
Clonality: monoclonal
Clone: BC96
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity: