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Description: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
Référence Produit: BOSSBS-1720R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Référence Produit: BOSSBS-10152R-CY5
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Nunc™, Couvercle pour plaques, Couvercle pour plaques MicroWell 96 puits, avec coins coupés et anneaux de condensation, incolore, Non stérile
Référence Produit: NUNC253624
UOM: 1 * 100 Pce
Fournisseur: Thermo Fisher Scientific

Certificats. Environmentally Preferable


Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Référence Produit: BOSSBS-10152R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Avec les plaques de culture multi-puits VWR®, vous avez le choix entre plusieurs traitements de surface.
Référence Produit: 734-2777
UOM: 1 * 100 Pce
Fournisseur: VWR Collection

Certificats. Environmentally Preferable


Description: Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-270 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin. Talin and vinculin have been shown to interact with each other and both have been proposed to be involved in generating the transmembrane connection, between the extracellular matrix and the cytoskeleton, that occurs at adhesion plaques. At physiological ionic strength, talin is an elongate, flexible, monomeric protein with the ability to self-associate into dimers at higher protein concentrations.
Référence Produit: BOSSBS-3619R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-270 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin. Talin and vinculin have been shown to interact with each other and both have been proposed to be involved in generating the transmembrane connection, between the extracellular matrix and the cytoskeleton, that occurs at adhesion plaques. At physiological ionic strength, talin is an elongate, flexible, monomeric protein with the ability to self-associate into dimers at higher protein concentrations.
Référence Produit: BOSSBS-3619R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Rotor à plaques de microtitrage, 6 places, aluminium anodisé, contenant 6 plaques standard ou 3 plaques de microtitrage à puits profonds, Pour: Labconco CentriVap®
Référence Produit: 531-1074
UOM: 1 * 1 Pce
Fournisseur: LABCONCO


Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Référence Produit: BOSSBS-6585R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Universal lids and cap mats for square microplates.
Référence Produit: AGLS202497-100
UOM: 1 * 100 Pce
Fournisseur: AGILENT

New Product


Description: La gamme de plaques CCM LuxPlate® haute fluorescence contient une quantité accrue d'indicateur de fluorescence, ce qui permet d'identifier aisément les faibles concentration en analytes. En outre, la quantité de liant ajoutée est également plus élevée, ce qui augmente considérablement la luminosité de la plaque CCM, ainsi que la stabilité et la solidité de la surface.
Référence Produit: 1.05805.0001
UOM: 1 * 25 Pce
Fournisseur: Merck

Description: Plaques chauffantes compactes avec plateau en céramique résistant aux produits chimiques. Le panneau de commande surélevé est peu exposé aux éclaboussures et permet une lecture et un ajustement faciles de la température. Les unités comportent un affichage numérique du code d’erreur et un indicateur « chaud » sur le dessus pour avertir les utilisateurs que la surface est chaude.
Référence Produit: 453-0050
UOM: 1 * 1 Pce
Fournisseur: VWR Collection


Description: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
Référence Produit: BOSSBS-11643R-A750
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
Référence Produit: BOSSBS-11643R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss


Description: α-synuclein, an acidic neuronal protein of 140 aa, has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and to be an important regulatory component of vesicular transport in neuronal cells. The NAC (non-Aβ component of amyloid plaques) domain (aa 61-95) of α-synuclein is an highly amyloidogenic peptide which was first identified associated with senile plaques in the Alzheimer's disease brain.
Référence Produit: ENZOALX804656R100
UOM: 1 * 100 µl
Fournisseur: ENZO LIFE SCIENCES


Description: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Référence Produit: BOSSBS-6585R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss


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