Imprimer
Filtrer les Résultats Trier par

Sort Results

Vue liste Nouvelle Vue
SearchResultCount:"93585"

Evaluer les résultats de votre recherche

Image Unavailable-BOSSBS-2763R-HRP

Anti-CRK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
Référence Produit: BOSSBS-2763R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6818R-CY5.5

Anti-MAGEA12 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Not known, though may play a role in tumor transformation or aspects of tumor progression.Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
Référence Produit: BOSSBS-6818R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-0480R-CY3

Anti-IFNG Rabbit Polyclonal Antibody (Cy3®)

Description: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Référence Produit: BOSSBS-0480R-CY3
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-0481R-CY7

Anti-IFNG Rabbit Polyclonal Antibody (Cy7®)

Description: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Référence Produit: BOSSBS-0481R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6874R-CY7

Anti-CAT Rabbit Polyclonal Antibody (Cy7®)

Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Référence Produit: BOSSBS-6874R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6874R-CY5

Anti-CAT Rabbit Polyclonal Antibody (Cy5®)

Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Référence Produit: BOSSBS-6874R-CY5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6874R-CY5.5

Anti-CAT Rabbit Polyclonal Antibody (Cy5.5®)

Description: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Référence Produit: BOSSBS-6874R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6136R-HRP

Anti-AdV 5 E1A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
Référence Produit: BOSSBS-6136R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-USBIT8250-50H

Anti-TGFBR3 Rabbit Polyclonal Antibody

Description: Anti-TGFBR3 Rabbit Polyclonal Antibody
Référence Produit: USBIT8250-50H
UOM: 1 * 50 µG
Fournisseur: US Biological
Image Unavailable-BOSSBS-2763R-A555

Anti-CRK Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
Référence Produit: BOSSBS-2763R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-2763R-FITC

Anti-CRK Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
Référence Produit: BOSSBS-2763R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-1684R-A488

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
Référence Produit: BOSSBS-1684R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-USBIT8666-40A-APC

Anti-TRRAP Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Description: Anti-TRRAP Rabbit Polyclonal Antibody (APC (Allophycocyanin))
Référence Produit: USBIT8666-40A-APC
UOM: 1 * 200 µl
Fournisseur: US Biological
Image Unavailable-BOSSBS-0100R-HRP

Anti-TGFB2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
Référence Produit: BOSSBS-0100R-HRP
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-0100R-A555

Anti-TGFB2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
Référence Produit: BOSSBS-0100R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6043R-A555

Anti-NBL1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
Référence Produit: BOSSBS-6043R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
1 - 16 of 93 585